slightly off topic but CagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it
#cagrilintide 2025-10-08
Wednesday19 messages5 participantstimes are UTC
Highlights from this day
- dublin_dose — slightly off topic but CagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it 19:13
- snac_and_water — is the combination just the two dosed together or a single formulation 21:46
- salt_bridge — £38 for a 40 vial and it lasts me longer than the GLP-1 does at my doses 22:20
- salt_bridge — the fullness thing is the part people describe differently, food stops being interesting rather than repellent 22:41
did the combination change your GI compared to the GLP-1 alone
how slow are people titrating this compared to tirzepatide
monotherapy did work for me, just slower and smaller than i expected
fullness rather than nausea
anyone dosing this on a different day to their retatrutide
amylin not glp-1
nobody should copy my schedule, im describing it because people asked what a slow ramp looks like
stopped for 19 months and the fullness went within a fortnight of the last dose
*Medutest not the other one
thats the phase 3 one
changed my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing
cant separate them
sorry to jump in weekly for me, same day every week, no reason beyond habit
[edited]is the combination just the two dosed together or a single formulation
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held mine a while
£38 for a 40 vial and it lasts me longer than the GLP-1 does at my doses
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the fullness thing is the part people describe differently, food stops being interesting rather than repellent
REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work