different not less
#cagrilintide 2025-08-18
Monday20 messages5 participantstimes are UTC
Highlights from this day
- hard_stop_hal — sorry to jump in i titrated over twice as many weeks as i did on semaglutide and that was right for me REDEFINE is the phase 3 programme, most of what gets quoted… 17:35
- hard_stop_hal — has REDEFINE reported or are people quoting earlier work 17:37
- sgp_subq — weekly for me, same day every week, no reason beyond habit the reason nausea reads differently is timing, mine arrived on the second day rather than the first 18:08
- hard_stop_hal — is anyone running this on its own or is it all CagriSema in here 18:20
- septum_sal — monotherapy did work for me, just slower and smaller than i expected, i could be wrong 19:36
the fullness thing is the part people describe differently, food stops being interesting rather than repellent
stopped for 25 months and the fullness went within a fortnight of the last dose, we shall see
sorry to jump in i titrated over twice as many weeks as i did on semaglutide and that was right for me
REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work
if youre used to GLP-1 titration steps this feels absurdly cautious and i still do it that way
has REDEFINE reported or are people quoting earlier work
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held mine a while
weekly for me, same day every week, no reason beyond habit
the reason nausea reads differently is timing, mine arrived on the second day rather than the first
*VendorInvestigate not the other one
did anyone find monotherapy underwhelming
the combination is the thing with trial data behind it, monotherapy in here is mostly us guessing
is anyone running this on its own or is it all CagriSema in here
monotherapy here
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REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work
amylin analogue, so its not a GLP-1 at all right
monotherapy did work for me, just slower and smaller than i expected, i could be wrong
the slower titration in here is community habit as much as anything, the trials had their own schedule, not advice obviously
£38 for a 30 vial and it lasts me longer than the GLP-1 does at my doses
coming back to this i said earlier this year that monotherapy did nothing for me, and at a higher dose it did something
amylin not glp-1