does the GIP arm actually explain the easier nausea or is that hand waving
#tirzepatide 2026-06-27
- meniscus_mel — unrelated but held 10 for 17 months and lost 28kg over that stretch, slow and boring and fine 13:51
- slow.taper — back after 19 months, do i restart at 2.5 or pick up near where i left off 14:14
- slow.taper — right so at 15 the GI came back for me, so my easier profile claim only applies below that 14:51
- nhs_pathway_nell — the two compounds arent interchangeable week for week even if the effect ends up similar i went to 15 and came back to 10, more suppression wasnt more useful for me 16:04
- nhs_pathway_nell — the switch felt like a step down at first and then caught up around week 20 SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up 16:21
i log everything and my appetite curve looks flatter across the week than my semaglutide log did, anyway
15 is the top
did anybody switch back to semaglutide after trying this
SURMOUNT is weight
easier gi for me
anyone stopped at 10 and stayed there for months
[edited]unrelated but held 10 for 17 months and lost 28kg over that stretch, slow and boring and fine
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
back after 19 months, do i restart at 2.5 or pick up near where i left off
12 did nothing extra over 10 for me and that still holds a year later
folklore probably
right so at 15 the GI came back for me, so my easier profile claim only applies below that
ok so the sweet spot thing is survivorship, the people it worked for stayed and said so
dual agonist, GIP as well as GLP-1, thats the whole difference in one line, thats just me
if youre coming off semaglutide the honest answer is start low and find out, theres no table
at 0.25 my appetite is gone entirely, did anyone go down rather than up
[edited]the two compounds arent interchangeable week for week even if the effect ends up similar
i went to 15 and came back to 10, more suppression wasnt more useful for me
the 2.5 to 5 step was the roughest one for me and everything after was easier
€55 for a 30 vial is roughly what ive paid for the last year
same plateau here
the switch felt like a step down at first and then caught up around week 20
SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
10 was enough
checked the units twice
is the 15 vial the common one or do people use 20
7.5 gang
how many weeks at 7.5 before you knew it was enough
titrate slow
[edited]