im at 15 and thinking about 10, did anyone gain anything from that step
#tirzepatide 2026-06-05
Friday52 messages11 participantstimes are UTC
Highlights from this day
- sharps_bin_sid — 40 units of a 2.5 solution is a lot of volume and i check that one twice every single time, take that with a pinch of salt 21:23
- noct.titrate — the 2.5 to 5 step was the roughest one for me and everything after was easier, n of 1 obviously 22:52
- VialBot — Verification log updated: GL Biochem — evidence added, status unchanged. 23:15
the two compounds arent interchangeable week for week even if the effect ends up similar
12 did nothing extra over 10 for me and that still holds a year later, from memory
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
40 units of a 2.5 solution is a lot of volume and i check that one twice every single time, take that with a pinch of salt
🙏9🤝7
7.5 gang
the trials titrated every four weeks to a target, most people here stop at whatever works
❤️1
the sweet spot thing is survivorship, the people it worked for stayed and said so
anyone tracked whether the GI difference held at the top doses
the sweet spot argument is really about effect per side effect, not a magic number
why does everyone talk about 7.5 and not 10
held 10 for 13 months and lost 38kg over that stretch, slow and boring and fine
how many weeks at 7.5 before you knew it was enough
is SURMOUNT-OSA the sleep apnoea one
SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
how did people handle the 2.5 to 5 jump
👍1💀11
i went to 15 and came back to 10, more suppression wasnt more useful for me, someone check my working
switched last year
licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
at 12 my appetite is gone entirely, did anyone go down rather than up
changed my mind about needing 15, i was chasing a number rather than an outcome
back after 25 months, do i restart at 2.5 or pick up near where i left off
does switching from semaglutide need a gap or do you just start
update on the earlier thing i sat at 7.5 for 13 months and never needed more, which is where the folklore comes from
medutest-report-f-1330.pdf
3 pages · 462 KB · not retained in the public archive
easier gi for me
switched from 1.7 semaglutide and started at 2.5, took the slow route, never regretted it
👀5😂10
New independent result logged — MKM, lot SG-1177, purity 96.8% (Medutest).
❤️3👀2
whats the top licensed dose, 15 or does it go higher
did going from 0.5 semaglutide to 5 of this feel like a step down for anyone
🎉3😂4❤️5
anyone got a 2.5 recon they like for the 20 vials
plateaued at 11 weeks the same way i did on semaglutide, so i doubt its compound specific
SURMOUNT-1 versus SURPASS-2, which one was the weight trial
the 10 vial in 5ml gives 8mg/ml which puts 0.5 on 20 units, nice round numbers
checked the units twice
same plateau here
5 was where i first noticed it properly, 2.5 did almost nothing for me
anyone stopped at 10 and stayed there for months
went back to semaglutide after 7 months because the cost difference mattered more than the GI
did anyone find the GI easier than semaglutide at an equivalent effect
does the appetite effect feel different or just stronger
did anyone go past 15 and was there any point to it
📈1
the 2.5 to 5 step was the roughest one for me and everything after was easier, n of 1 obviously
❤️4🙏5⚠️15
start low anyway
🔥7
5 did nothing
if youre coming off semaglutide the honest answer is start low and find out, theres no table
€240 for a 30 vial is roughly what ive paid for the last year
[edited]10 was enough
Verification log updated: GL Biochem — evidence added, status unchanged.
💀18
folklore probably
how long before the dual thing was noticeable to you
15 is the top
*Medutest not the other one