does switching from semaglutide need a gap or do you just start
#tirzepatide 2026-06-04
Thursday24 messages5 participantstimes are UTC
Highlights from this day
- unsolicited_dm — no gap when i switched, took the last semaglutide dose and started this a week later 19:14
- madrid_mg — the switch felt like a step down at first and then caught up around week 30, thats one data point 20:18
- madrid_mg — the 2.5 to 5 step was the roughest one for me and everything after was easier 20:21
went back to semaglutide after 6 months because the cost difference mattered more than the GI
no gap when i switched, took the last semaglutide dose and started this a week later
🧊4🧪1
at 7.5 my appetite went completely and i dropped back a step, eating nothing isnt a win
switched last year
easier gi for me
👍3😂10
no clean conversion
7.5 gang
held 10 for 8 months and lost 47kg over that stretch, slow and boring and fine
checked the units twice
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
😂1
SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted
unsolicited_dmwent back to semaglutide after 6 months because the cost difference mattered more than…
dual agonist, GIP as well as GLP-1, thats the whole difference in one line
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the switch felt like a step down at first and then caught up around week 30, thats one data point
👍9🧊2📉7
the 2.5 to 5 step was the roughest one for me and everything after was easier
🧊15🧪3📉9
changed my mind about needing 15, i was chasing a number rather than an outcome
right so whats the plateau pattern here, same as semaglutide or different
the GI difference held for me right up to 15, which isnt what a couple of people here found
titrate slow
5 did nothing
15 is the top
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
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GIP plus GLP-1
📈4🤝10
did anyone go past 15 and was there any point to it