SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted
chromatogram-overlay.png
1240 × 720 · 835 KB · not retained in the public archive
#tirzepatide 2026-05-30
Saturday26 messages4 participantstimes are UTC
Highlights from this day
- maintenance_mo — SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted 15:18
- lisbon_lot — did anybody switch back to semaglutide after trying this 15:43
- area_percent — my Medutest result on a FGP vial came in at 98.6 which is why i keep buying from them 17:07
- gall_bladder_gav — there is no clean conversion between the two, anyone giving you a ratio is guessing, thats one data point 17:10
did going from 1.7 semaglutide to 5 of this feel like a step down for anyone
slightly off topic but i went to 15 and came back to 10, more suppression wasnt more useful for me
did anybody switch back to semaglutide after trying this
📈18⚠️15🙏5
the switch felt like a step down at first and then caught up around week 29
the 15 vial in 5ml gives 4mg/ml which puts 2.4 on 40 units, nice round numbers
the two compounds arent interchangeable week for week even if the effect ends up similar, thats one data point
no clean conversion
🎉3👀12💀9
titrate slow
if youre coming off semaglutide the honest answer is start low and find out, theres no table
*Janoshik not the other one
did anyone find the GI easier than semaglutide at an equivalent effect
how did people handle the 2.5 to 5 jump
⚠️5
€185 for a 5 vial is roughly what ive paid for the last year
my Medutest result on a FGP vial came in at 98.6 which is why i keep buying from them
there is no clean conversion between the two, anyone giving you a ratio is guessing, thats one data point
⚠️9❤️6
start low anyway
switched last year
whats the top licensed dose, 15 or does it go higher
folklore probably
5 was where i first noticed it properly, 2.5 did almost nothing for me
10 was enough
slightly off topic but went back to semaglutide after 10 months because the cost difference mattered more than the GI, thats just me
coming back to this i sat at 7.5 for 18 months and never needed more, which is where the folklore comes from
at 15 the GI came back for me, so my easier profile claim only applies below that
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect