start low anyway
#tirzepatide 2026-04-26
Sunday28 messages7 participantstimes are UTC
Highlights from this day
- hard_stop_hal — the 2 vial in 2ml gives 10mg/ml which puts 0.25 on 25 units, nice round numbers 22:22
- hard_stop_hal — the GI difference held for me right up to 15, which isnt what a couple of people here found 22:37
- eight_mm — the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact 22:41
does switching from semaglutide need a gap or do you just start
[edited]folklore probably
the 2 vial in 2ml gives 10mg/ml which puts 0.25 on 25 units, nice round numbers
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SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted
the two compounds arent interchangeable week for week even if the effect ends up similar
if youre coming off semaglutide the honest answer is start low and find out, theres no table
$55 for a 2 vial is roughly what ive paid for the last year
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no clean conversion
no gap when i switched, took the last semaglutide dose and started this a week later
40 units of a 4 solution is a lot of volume and i check that one twice every single time
the GI difference held for me right up to 15, which isnt what a couple of people here found
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the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
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5 was where i first noticed it properly, 2.5 did almost nothing for me
did anyone go past 15 and was there any point to it
licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
*week 9 not week 3
7.5 gang
peptidemeter-summary-c-4402.pdf
2 pages · 926 KB · not retained in the public archive
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the trials titrated every four weeks to a target, most people here stop at whatever works
i log everything and my appetite curve looks flatter across the week than my semaglutide log did
i argued the sweet spot was nonsense and then spent 11 months at 7.5 not needing more
i went to 15 and came back to 10, more suppression wasnt more useful for me
im at 1.7 and thinking about 1, did anyone gain anything from that step
the sweet spot thing is survivorship, the people it worked for stayed and said so, take that with a pinch of salt
the 2.5 to 5 step was the roughest one for me and everything after was easier
the 2.5 to 5 step was the roughest one for me and everything after was easier
back after 9 months, do i restart at 2.5 or pick up near where i left off
went back to semaglutide after 12 months because the cost difference mattered more than the GI
there is no clean conversion between the two, anyone giving you a ratio is guessing
slightly off topic but switched from 2 semaglutide and started at 2.5, took the slow route, never regretted it, we shall see
follow up the switch felt like a step down at first and then caught up around week 29
the sweet spot argument is really about effect per side effect, not a magic number