vialroom

#tirzepatide 2026-03-31

Tuesday20 messages7 participantstimes are UTC
Highlights from this day
  • VialBot — Purity check: no report on file for lot D-0718. Nothing logged either way. 13:16
  • pbs_pip — ok so the 40 vial in 1ml gives 8mg/ml which puts 7.5 on 50 units, nice round numbers 14:24
  • pbs_pip — sorry to jump in at 10 my appetite went completely and i dropped back a step, eating nothing isnt a win 15:11
  • karl_fischer — coming off semaglutide, is there a conversion or do i restart at 2.5 SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up 16:23
VV

i log everything and my appetite curve looks flatter across the week than my semaglutide log did

SV

i argued the sweet spot was nonsense and then spent 5 months at 7.5 not needing more

VB

Purity check: no report on file for lot D-0718. Nothing logged either way.

PP

ok so the 40 vial in 1ml gives 8mg/ml which puts 7.5 on 50 units, nice round numbers

📉8👀3🙏1
VV

held 10 for 13 months and lost 29kg over that stretch, slow and boring and fine

12 did nothing extra over 10 for me and that still holds a year later

PP

sorry to jump in at 10 my appetite went completely and i dropped back a step, eating nothing isnt a win

Cited study
Tirzepatide versus Semaglutide Once Weekly in Type 2 Diabetes (SURPASS-2)
New England Journal of Medicine · 2021
The head-to-head everyone quotes. Note the semaglutide comparator dose.
SV

did anyone find the GI easier than semaglutide at an equivalent effect

VV

no gap when i switched, took the last semaglutide dose and started this a week later

BB

sorry to jump in €72 for a 40 vial is roughly what ive paid for the last year

PP

did anybody switch back to semaglutide after trying this

folklore probably

the trials titrated every four weeks to a target, most people here stop at whatever works

KF

coming off semaglutide, is there a conversion or do i restart at 2.5
SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up

🎉18👀8