#tirzepatide 2026-03-23

Monday18 messages4 participantstimes are UTC

Highlights from this day

VialBot — Channel stats, last 30 days: 52 messages from 59 members. 20:36
no_appetite_nia — is SURMOUNT-OSA the sleep apnoea one 21:18
manila_meniscus — slightly off topic but my Janoshik result on a WXT vial came in at 98.6 which is why i keep buying from them 21:19
no_appetite_nia — the GI difference held for me right up to 15, which isnt what a couple of people here found 21:24
no_appetite_nia — i log everything and my appetite curve looks flatter across the week than my semaglutide log did 21:46

restarted at 2.5 after 23 months off and the first two doses reminded me why titration exists

Channel stats, last 30 days: 52 messages from 59 members.

switched last year

i sat at 7.5 for 14 months and never needed more, which is where the folklore comes from

at 10 my appetite is gone entirely, did anyone go down rather than up

quick one did anybody switch back to semaglutide after trying this

genuine question im at 1.7 and thinking about 2.5, did anyone gain anything from that step

[edited]

is SURMOUNT-OSA the sleep apnoea one

❤️1🤝8

slightly off topic but my Janoshik result on a WXT vial came in at 98.6 which is why i keep buying from them

follow up the switch felt like a step down at first and then caught up around week 5

the GI difference held for me right up to 15, which isnt what a couple of people here found

🧊1🔥3

i log everything and my appetite curve looks flatter across the week than my semaglutide log did

the sweet spot argument is really about effect per side effect, not a magic number

SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up

if youre coming off semaglutide the honest answer is start low and find out, theres no table

plateaued at 33 weeks the same way i did on semaglutide, so i doubt its compound specific

how did people handle the 2.5 to 5 jump

10 was enough

[edited]