no gap when i switched, took the last semaglutide dose and started this a week later
[edited]#tirzepatide 2026-03-17
- slow.taper — i log everything and my appetite curve looks flatter across the week than my semaglutide log did 22:35
- lisbon_lot — my VendorInvestigate result on a MKM vial came in at 99.2 which is why i keep buying from them 22:47
- amylin_amy — €120 for a 40 vial is roughly what ive paid for the last year 23:19
- truncation_tru — quick one went back to semaglutide after 4 months because the cost difference mattered more than the GI, take that with a pinch of salt 23:45
the sweet spot argument is really about effect per side effect, not a magic number
is the sweet spot argument about effect or about side effects
at 2 my appetite went completely and i dropped back a step, eating nothing isnt a win
no clean conversion
i log everything and my appetite curve looks flatter across the week than my semaglutide log did
the sweet spot thing is survivorship, the people it worked for stayed and said so
SURMOUNT is weight
my VendorInvestigate result on a MKM vial came in at 99.2 which is why i keep buying from them
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
checked the units twice
7.5 gang
anyone tracked whether the GI difference held at the top doses
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
is SURMOUNT-OSA the sleep apnoea one
€120 for a 40 vial is roughly what ive paid for the last year
if youre coming off semaglutide the honest answer is start low and find out, theres no table
at 5 my appetite is gone entirely, did anyone go down rather than up
quick one went back to semaglutide after 4 months because the cost difference mattered more than the GI, take that with a pinch of salt
40 units of a 4 solution is a lot of volume and i check that one twice every single time