SURMOUNT is weight
#tirzepatide 2026-02-03
- gip_glp_gil — is 7.5 really the sweet spot or is that just channel folklore 10:32
- slow.taper — changed my mind about needing 15, i was chasing a number rather than an outcome 11:50
- slow.taper — for the archive plateaued at 32 weeks the same way i did on semaglutide, so i doubt its compound specific 11:51
- declared_value — coming back to this i went to 15 and came back to 10, more suppression wasnt more useful for me 12:19
- pharmac_pen — unrelated but is the sweet spot argument about effect or about side effects 12:38
how did people handle the 2.5 to 5 jump
is 7.5 really the sweet spot or is that just channel folklore
£55 for a 20 vial is roughly what ive paid for the last year
[edited]start low anyway
at 2.4 my appetite is gone entirely, did anyone go down rather than up
same plateau here
the GI difference held for me right up to 15, which isnt what a couple of people here found
how many weeks at 7.5 before you knew it was enough
changed my mind about needing 15, i was chasing a number rather than an outcome
for the archive plateaued at 32 weeks the same way i did on semaglutide, so i doubt its compound specific
[edited]15 is the top
is the 20 vial the common one or do people use 30
coming back to this i went to 15 and came back to 10, more suppression wasnt more useful for me
coming back to this did anyone go past 15 and was there any point to it
is there a reason to titrate slower than the four week schedule
unrelated but is the sweet spot argument about effect or about side effects
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |