titrate slow
#tirzepatide 2025-11-30
Sunday33 messages7 participantstimes are UTC
Highlights from this day
- protein_floor — coming off semaglutide, is there a conversion or do i restart at 2.5 plateaued at 22 weeks the same way i did on semaglutide, so i doubt its compound specific 15:50
- protein_floor — i log everything and my appetite curve looks flatter across the week than my semaglutide log did 15:51
- pia_plateaus — i argued the sweet spot was nonsense and then spent 1 months at 7.5 not needing more, i think 16:31
- LC_MS_Lena — the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact, still working it out 16:58
- LC_MS_Lena — my Janoshik result on a QSC vial came in at 96.8 which is why i keep buying from them 17:00
SURMOUNT-1 versus SURPASS-2, which one was the weight trial
GIP plus GLP-1
switched last year
held 10 for 13 months and lost 16kg over that stretch, slow and boring and fine
10 was enough
coming off semaglutide, is there a conversion or do i restart at 2.5
plateaued at 22 weeks the same way i did on semaglutide, so i doubt its compound specific
🧊15👍10
i log everything and my appetite curve looks flatter across the week than my semaglutide log did
at 15 my appetite went completely and i dropped back a step, eating nothing isnt a win
folklore probably
i argued the sweet spot was nonsense and then spent 1 months at 7.5 not needing more, i think
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
did going from 2 semaglutide to 5 of this feel like a step down for anyone
ok so does switching from semaglutide need a gap or do you just start
start low anyway
whats the top licensed dose, 15 or does it go higher
5 did nothing
plateaued at 11 weeks the same way i did on semaglutide, so i doubt its compound specific
€55 for a 15 vial is roughly what ive paid for the last year
the two compounds arent interchangeable week for week even if the effect ends up similar
dual agonist, GIP as well as GLP-1, thats the whole difference in one line
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact, still working it out
my Janoshik result on a QSC vial came in at 96.8 which is why i keep buying from them
the 5 vial in 5ml gives 2.5mg/ml which puts 0.5 on 8 units, nice round numbers
15 is the top
📉6🧊1🔥5
7.5 gang
checked the units twice
🙏8🧊10
the 2.5 to 5 step was the roughest one for me and everything after was easier
how long before the dual thing was noticeable to you
anyone got a 2 recon they like for the 2 vials
restarted at 2.5 after 19 months off and the first two doses reminded me why titration exists
easier gi for me