whats the top licensed dose, 15 or does it go higher
SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
🧊16⚠️16
#tirzepatide 2025-11-23
Sunday43 messages10 participantstimes are UTC
Highlights from this day
- bo_bloodwork — whats the top licensed dose, 15 or does it go higher SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up 22:24
- HPLC_Hank — at 2.4 my appetite is gone entirely, did anyone go down rather than up 22:33
- nine_nine_one — coming off semaglutide, is there a conversion or do i restart at 2.5 22:41
- cricket_or_footy — plateaued at 8 weeks the same way i did on semaglutide, so i doubt its compound specific 22:51
no clean conversion
genuine question switched from 7.5 semaglutide and started at 2.5, took the slow route, never regretted it
genuine question is SURMOUNT-OSA the sleep apnoea one
did anyone find the GI easier than semaglutide at an equivalent effect
at 2.4 my appetite is gone entirely, did anyone go down rather than up
❤️18👀2💀11
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
follow up anyone got a 8 recon they like for the 40 vials
start low anyway
🔥13
coming off semaglutide, is there a conversion or do i restart at 2.5
🎉6
SURMOUNT is weight
🙏7
folklore probably
sorry to jump in whats the plateau pattern here, same as semaglutide or different
12 did nothing extra over 10 for me and that still holds a year later, i think
plateaued at 8 weeks the same way i did on semaglutide, so i doubt its compound specific
❤️15📈3
7.5 gang
sorry to jump in did going from 5 semaglutide to 5 of this feel like a step down for anyone
dual agonist, GIP as well as GLP-1, thats the whole difference in one line
i went to 15 and came back to 10, more suppression wasnt more useful for me
switched last year
genuine question the 2.5 to 5 step was the roughest one for me and everything after was easier
easier gi for me
slightly off topic but is the 15 vial the common one or do people use 10
i log everything and my appetite curve looks flatter across the week than my semaglutide log did
the sweet spot argument is really about effect per side effect, not a magic number
changed my mind about needing 15, i was chasing a number rather than an outcome
genuine question how many weeks at 7.5 before you knew it was enough
10 was enough
if youre coming off semaglutide the honest answer is start low and find out, theres no table
i sat at 7.5 for 24 months and never needed more, which is where the folklore comes from
15 is the top
same plateau here
🎉11
GIP plus GLP-1
does switching from semaglutide need a gap or do you just start
ok so the trials titrated every four weeks to a target, most people here stop at whatever works
at 15 the GI came back for me, so my easier profile claim only applies below that
did anyone go past 15 and was there any point to it
at 1 my appetite went completely and i dropped back a step, eating nothing isnt a win
the switch felt like a step down at first and then caught up around week 2
does the appetite effect feel different or just stronger
back after 15 months, do i restart at 2.5 or pick up near where i left off
the sweet spot thing is survivorship, the people it worked for stayed and said so
does the GIP arm actually explain the easier nausea or is that hand waving
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact