#tirzepatide 2025-10-22

SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted

SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up

titrate slow

folklore probably

anyone stopped at 10 and stayed there for months

12 did nothing extra over 10 for me and that still holds a year later

at 15 the GI came back for me, so my easier profile claim only applies below that

dual agonist, GIP as well as GLP-1, thats the whole difference in one line

anyone tracked whether the GI difference held at the top doses

5 did nothing

10 was enough

if youre coming off semaglutide the honest answer is start low and find out, theres no table

ok so 40 units of a 8 solution is a lot of volume and i check that one twice every single time

back after 15 months, do i restart at 2.5 or pick up near where i left off

the two compounds arent interchangeable week for week even if the effect ends up similar

whats the plateau pattern here, same as semaglutide or different

15 is the top

the sweet spot thing is survivorship, the people it worked for stayed and said so

same plateau here

is there a reason to titrate slower than the four week schedule

how did people handle the 2.5 to 5 jump