sorry to jump in the sweet spot thing is survivorship, the people it worked for stayed and said so
#tirzepatide 2025-10-17
- week_three_wall — i sat at 7.5 for 15 months and never needed more, which is where the folklore comes from 18:52
- ferrous_ash — the two compounds arent interchangeable week for week even if the effect ends up similar, for what its worth 19:22
- van_isle_vial — the 20 vial in 2.5ml gives 8mg/ml which puts 15 on 25 units, nice round numbers 20:38
- lyophile_liv — i log everything and my appetite curve looks flatter across the week than my semaglutide log did 20:40
- lyophile_liv — SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up 20:49
the GI difference held for me right up to 15, which isnt what a couple of people here found
i sat at 7.5 for 15 months and never needed more, which is where the folklore comes from
the two compounds arent interchangeable week for week even if the effect ends up similar, for what its worth
if youre coming off semaglutide the honest answer is start low and find out, theres no table
folklore probably
plateaued at 21 weeks the same way i did on semaglutide, so i doubt its compound specific
i went to 15 and came back to 10, more suppression wasnt more useful for me
5 was where i first noticed it properly, 2.5 did almost nothing for me, i think
the 20 vial in 2.5ml gives 8mg/ml which puts 15 on 25 units, nice round numbers
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
changed my mind about needing 15, i was chasing a number rather than an outcome
i log everything and my appetite curve looks flatter across the week than my semaglutide log did
SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up