back after 24 months, do i restart at 2.5 or pick up near where i left off
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#tirzepatide 2025-08-19
Tuesday45 messages11 participantstimes are UTC
Highlights from this day
- nine_nine_one — back after 24 months, do i restart at 2.5 or pick up near where i left off 15:13
- VialBot — Verification log updated: CPC — evidence added, status unchanged. 17:16
- VialBot — Reminder set. I will post here in 8 days. 17:26
- swirl_not_shake — is there a reason to titrate slower than the four week schedule 17:52
- split_shipment — the two compounds arent interchangeable week for week even if the effect ends up similar 20:07
easier gi for me
anyone tracked whether the GI difference held at the top doses
switched last year
start low anyway
went back to semaglutide after 23 months because the cost difference mattered more than the GI
how many weeks at 7.5 before you knew it was enough
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did anyone find the GI easier than semaglutide at an equivalent effect
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
how did people handle the 2.5 to 5 jump
why does everyone talk about 7.5 and not 10
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SURMOUNT is weight
slightly off topic but dual agonist, GIP as well as GLP-1, thats the whole difference in one line
coming back to this the 2.5 to 5 step was the roughest one for me and everything after was easier
restarted at 2.5 after 26 months off and the first two doses reminded me why titration exists, for what its worth
update on the earlier thing GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
whats the plateau pattern here, same as semaglutide or different
anyone got a 2 recon they like for the 2 vials
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did going from 12 semaglutide to 5 of this feel like a step down for anyone
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the trials titrated every four weeks to a target, most people here stop at whatever works, i think
Verification log updated: CPC — evidence added, status unchanged.
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at 1 my appetite went completely and i dropped back a step, eating nothing isnt a win
i sat at 7.5 for 18 months and never needed more, which is where the folklore comes from
Reminder set. I will post here in 8 days.
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same plateau here
40 units of a 10 solution is a lot of volume and i check that one twice every single time
the GI difference held for me right up to 15, which isnt what a couple of people here found
[edited]the 5 vial in 1.5ml gives 8mg/ml which puts 12 on 40 units, nice round numbers
sorry to jump in licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
15 is the top
is there a reason to titrate slower than the four week schedule
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does the appetite effect feel different or just stronger
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plateaued at 32 weeks the same way i did on semaglutide, so i doubt its compound specific
did anyone go past 15 and was there any point to it
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SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
sorry to jump in held 10 for 16 months and lost 48kg over that stretch, slow and boring and fine
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my Medutest result on a SWB vial came in at 99.2 which is why i keep buying from them
is the sweet spot argument about effect or about side effects
£55 for a 20 vial is roughly what ive paid for the last year
at 15 the GI came back for me, so my easier profile claim only applies below that
10 was enough
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12 did nothing extra over 10 for me and that still holds a year later
the two compounds arent interchangeable week for week even if the effect ends up similar
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i argued the sweet spot was nonsense and then spent 9 months at 7.5 not needing more, ill dig out the number
switched from 2.5 semaglutide and started at 2.5, took the slow route, never regretted it
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7.5 gang