vialroom

#tirzepatide 2025-06-07

Saturday23 messages5 participantstimes are UTC
Highlights from this day
  • reship_rita — 5 was where i first noticed it properly, 2.5 did almost nothing for me 19:52
  • reship_rita — the sweet spot thing is survivorship, the people it worked for stayed and said so 20:03
  • maintenance_mo — how many weeks at 7.5 before you knew it was enough 20:20
  • rotterdam_recon — SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up 21:02
RR

i log everything and my appetite curve looks flatter across the week than my semaglutide log did

5 was where i first noticed it properly, 2.5 did almost nothing for me

fridge-temps.csv
656 rows · not retained in the public archive
👀12💀6
NP

the GI difference held for me right up to 15, which isnt what a couple of people here found

RR

the sweet spot thing is survivorship, the people it worked for stayed and said so

😂2❤️18

40 units of a 2.5 solution is a lot of volume and i check that one twice every single time

MM

i argued the sweet spot was nonsense and then spent 2 months at 7.5 not needing more

wk 1-4    2.5mg
wk 5-8    5.0mg
wk 9-20   7.5mg   <- stayed here
wk 21-24  10.0mg  (no extra benefit for me)
wk 25+    7.5mg   (came back down)

how many weeks at 7.5 before you knew it was enough

🔥6⚠️11
RR

there is no clean conversion between the two, anyone giving you a ratio is guessing

👍1📈1❤️3

no clean conversion

🧊17💀1
MM

sorry to jump in €94 for a 15 vial is roughly what ive paid for the last year

🧊3
RR

licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does

RR

SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up

Cited study
Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1)
New England Journal of Medicine · 2022
72 weeks, tirzepatide 5, 10 and 15mg against placebo.
🧪1612😂5
RR

the two compounds arent interchangeable week for week even if the effect ends up similar

RR

sorry to jump in is the 30 vial the common one or do people use 10
the sweet spot argument is really about effect per side effect, not a magic number

MM

the 15 vial in 1ml gives 5mg/ml which puts 2.5 on 12 units, nice round numbers

🙏3📉12👀1

same plateau here