update on the earlier thing licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
👍18
#tirzepatide 2025-06-06
Friday38 messages8 participantstimes are UTC
Highlights from this day
- appetite_back — update on the earlier thing licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does 19:19
- bengaluru_bac — unrelated but anyone stopped at 10 and stayed there for months 19:39
- bengaluru_bac — the 2.5 to 5 step was the roughest one for me and everything after was easier 21:08
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
19:29ferrous_ash pinned a message
40 units of a 8 solution is a lot of volume and i check that one twice every single time, anyway
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)no gap when i switched, took the last semaglutide dose and started this a week later
unrelated but anyone stopped at 10 and stayed there for months
🔥2🧪17
is the 2 vial the common one or do people use 5
[edited]€55 for a 15 vial is roughly what ive paid for the last year
switched last year
👍5👀13💀2
ok so the sweet spot argument is really about effect per side effect, not a magic number
titrate slow
the 20 vial in 0.5ml gives 2mg/ml which puts 7.5 on 15 units, nice round numbers
whats the top licensed dose, 15 or does it go higher
there is no clean conversion between the two, anyone giving you a ratio is guessing, someone check my working
did going from 0.25 semaglutide to 5 of this feel like a step down for anyone
anyone got a 2.5 recon they like for the 40 vials
dual agonist, GIP as well as GLP-1, thats the whole difference in one line
is SURMOUNT-OSA the sleep apnoea one
at 15 the GI came back for me, so my easier profile claim only applies below that
my VendorInvestigate result on a SGN vial came in at 96.8 which is why i keep buying from them, n of 1 obviously
at 15 the GI came back for me, so my easier profile claim only applies below that
back after 20 months, do i restart at 2.5 or pick up near where i left off
i argued the sweet spot was nonsense and then spent 19 months at 7.5 not needing more
how many weeks at 7.5 before you knew it was enough
5 was where i first noticed it properly, 2.5 did almost nothing for me
the 2.5 to 5 step was the roughest one for me and everything after was easier
❤️18✅1
right so the two compounds arent interchangeable week for week even if the effect ends up similar
❤️2
is the sweet spot argument about effect or about side effects
does switching from semaglutide need a gap or do you just start
10 was enough
SURMOUNT-1 versus SURPASS-2, which one was the weight trial
the sweet spot thing is survivorship, the people it worked for stayed and said so
folklore probably
✅1
held 10 for 7 months and lost 47kg over that stretch, slow and boring and fine, for what its worth
🧪9
15 is the top
coming off semaglutide, is there a conversion or do i restart at 2.5
i argued the sweet spot was nonsense and then spent 15 months at 7.5 not needing more
SURMOUNT is weight
follow up at 12 my appetite went completely and i dropped back a step, eating nothing isnt a win
did anybody switch back to semaglutide after trying this