vialroom

#tirzepatide 2025-04-26

Saturday46 messages12 participantstimes are UTC
Highlights from this day
  • provincial_pat — i sat at 7.5 for 15 months and never needed more, which is where the folklore comes from 08:30
  • VialBot — New independent result logged — FGP, lot D-0718, purity 98.6% (Janoshik). 08:38
  • snac_and_water — at 1.7 my appetite went completely and i dropped back a step, eating nothing isnt a win, ask me again in a month 10:50
  • VialBot — Channel stats, last 30 days: 47 messages from 34 members. 10:53
RR

my VendorInvestigate result on a TFC vial came in at 98.1 which is why i keep buying from them

the two compounds arent interchangeable week for week even if the effect ends up similar

VB

Batch lookup A-2418: 5 independent reports on file, earliest 2025-01-20.

RR

right so restarted at 2.5 after 5 months off and the first two doses reminded me why titration exists
SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted

PS

while im here 5 was where i first noticed it properly, 2.5 did almost nothing for me

PP

the 2 vial in 1ml gives 10mg/ml which puts 2.4 on 8 units, nice round numbers, happy to be corrected

PP

40 units of a 5 solution is a lot of volume and i check that one twice every single time

VB

New independent result logged — FGP, lot D-0718, purity 98.6% (Janoshik).

PS

there is no clean conversion between the two, anyone giving you a ratio is guessing

PP

at 15 the GI came back for me, so my easier profile claim only applies below that
12 did nothing extra over 10 for me and that still holds a year later

*that should say weekly

ST

coming off semaglutide, is there a conversion or do i restart at 2.5
the sweet spot thing is survivorship, the people it worked for stayed and said so

SA

does the GIP arm actually explain the easier nausea or is that hand waving
the two compounds arent interchangeable week for week even if the effect ends up similar

SA

at 1.7 my appetite went completely and i dropped back a step, eating nothing isnt a win, ask me again in a month

👀2🤝18

is SURMOUNT-OSA the sleep apnoea one

VB

Channel stats, last 30 days: 47 messages from 34 members.

😂1👍10
SA

€72 for a 15 vial is roughly what ive paid for the last year

Cited study
Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1)
New England Journal of Medicine · 2022
72 weeks, tirzepatide 5, 10 and 15mg against placebo.
MM

switched from 12 semaglutide and started at 2.5, took the slow route, never regretted it

🔥1🧪7🧊1
HI

follow up the 2.5 to 5 step was the roughest one for me and everything after was easier

SB

i log everything and my appetite curve looks flatter across the week than my semaglutide log did

5 did nothing

SB

anyone stopped at 10 and stayed there for months

coa-f-1330.pdf
1 page · 279 KB · not retained in the public archive
ST

slightly off topic but plateaued at 7 weeks the same way i did on semaglutide, so i doubt its compound specific

A1

quick one the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact

i went to 15 and came back to 10, more suppression wasnt more useful for me

genuine question the GI difference held for me right up to 15, which isnt what a couple of people here found

SB

licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does

🎉3
ST

did going from 12 semaglutide to 5 of this feel like a step down for anyone

[edited]