the GI difference held for me right up to 15, which isnt what a couple of people here found
#tirzepatide 2025-02-23
- VialBot — Verification log updated: BCH — evidence added, status unchanged. 15:10
- HPLC_Hank — my PeptideMeter result on a GL Biochem vial came in at 96.8 which is why i keep buying from them 15:45
- forty_five_kg — 40 units of a 8 solution is a lot of volume and i check that one twice every single time 16:17
SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted
On this day 6 years ago this channel logged 132 messages.
at 15 the GI came back for me, so my easier profile claim only applies below that
i sat at 7.5 for 10 months and never needed more, which is where the folklore comes from
start low anyway
no clean conversion
folklore probably
same plateau here
plateaued at 12 weeks the same way i did on semaglutide, so i doubt its compound specific
the 10 vial in 5ml gives 5mg/ml which puts 7.5 on 5 units, nice round numbers
changed my mind about needing 15, i was chasing a number rather than an outcome
how many weeks at 7.5 before you knew it was enough
Verification log updated: BCH — evidence added, status unchanged.
went back to semaglutide after 5 months because the cost difference mattered more than the GI
if youre coming off semaglutide the honest answer is start low and find out, theres no table
£94 for a 40 vial is roughly what ive paid for the last year
my PeptideMeter result on a GL Biochem vial came in at 96.8 which is why i keep buying from them
easier gi for me
40 units of a 8 solution is a lot of volume and i check that one twice every single time
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
sorry to jump in the two compounds arent interchangeable week for week even if the effect ends up similar
does the appetite effect feel different or just stronger
at 15 my appetite went completely and i dropped back a step, eating nothing isnt a win
i argued the sweet spot was nonsense and then spent 21 months at 7.5 not needing more
the sweet spot thing is survivorship, the people it worked for stayed and said so
held 10 for 25 months and lost 37kg over that stretch, slow and boring and fine, ill dig out the number
10 was enough
genuine question does the GIP arm actually explain the easier nausea or is that hand waving
i went to 15 and came back to 10, more suppression wasnt more useful for me
whats the top licensed dose, 15 or does it go higher
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
is 7.5 really the sweet spot or is that just channel folklore
checked the units twice