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#tirzepatide 2025-02-22

Saturday21 messages4 participantstimes are UTC
Highlights from this day
  • step_one_sian — did going from 1 semaglutide to 5 of this feel like a step down for anyone 22:21
  • fridge_thermo — the GI difference held for me right up to 15, which isnt what a couple of people here found 23:02
  • gip_glp_gil — at 10 my appetite is gone entirely, did anyone go down rather than up 23:05
FT

the 2.5 to 5 step was the roughest one for me and everything after was easier

FT

dual agonist, GIP as well as GLP-1, thats the whole difference in one line

coa-h-2814.pdf
1 page · 386 KB · not retained in the public archive
FT

SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted

*Janoshik not the other one

did anybody switch back to semaglutide after trying this
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect

FT

back after 24 months, do i restart at 2.5 or pick up near where i left off

ok so does switching from semaglutide need a gap or do you just start

GG

12 did nothing extra over 10 for me and that still holds a year later

SO

did going from 1 semaglutide to 5 of this feel like a step down for anyone

📉6👀17🧪3

coming off semaglutide, is there a conversion or do i restart at 2.5

whats the plateau pattern here, same as semaglutide or different

40 units of a 2 solution is a lot of volume and i check that one twice every single time

did anyone go past 15 and was there any point to it

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SO

slightly off topic but the trials titrated every four weeks to a target, most people here stop at whatever works

SO

the sweet spot argument is really about effect per side effect, not a magic number

😂8
FT

SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up

the GI difference held for me right up to 15, which isnt what a couple of people here found

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VB

Inter-lab diff for lot SG-1177: 99.4% vs 98.6%. Within expected range.

GG

at 10 my appetite is gone entirely, did anyone go down rather than up

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