licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
#tirzepatide 2025-02-16
Sunday56 messages14 participantstimes are UTC
Highlights from this day
- mg_per_ml — my VendorInvestigate result on a SWB vial came in at 99 which is why i keep buying from them 20:03
- bea_reconstitutes — if youre coming off semaglutide the honest answer is start low and find out, theres no table 22:02
- fibre_first — at 2.4 my appetite is gone entirely, did anyone go down rather than up 23:46
i log everything and my appetite curve looks flatter across the week than my semaglutide log did
did anyone go past 15 and was there any point to it
how many weeks at 7.5 before you knew it was enough
ok so the sweet spot thing is survivorship, the people it worked for stayed and said so
im at 10 and thinking about 0.25, did anyone gain anything from that step
7.5 gang
🙏1👀1⚠️13
easier gi for me
no clean conversion
titrate slow
follow up anyone stopped at 10 and stayed there for months
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
€240 for a 15 vial is roughly what ive paid for the last year
40 units of a 4 solution is a lot of volume and i check that one twice every single time
how did people handle the 2.5 to 5 jump
SURMOUNT is weight
[edited]🔥7👀2
at 15 the GI came back for me, so my easier profile claim only applies below that
folklore probably
is the sweet spot argument about effect or about side effects
did going from 7.5 semaglutide to 5 of this feel like a step down for anyone
GIP plus GLP-1
the GI difference held for me right up to 15, which isnt what a couple of people here found, ill dig out the number
is SURMOUNT-OSA the sleep apnoea one
my VendorInvestigate result on a SWB vial came in at 99 which is why i keep buying from them
is the 20 vial the common one or do people use 10
held 10 for 2 months and lost 35kg over that stretch, slow and boring and fine
whats the top licensed dose, 15 or does it go higher
at 1 my appetite went completely and i dropped back a step, eating nothing isnt a win
the trials titrated every four weeks to a target, most people here stop at whatever works
15 is the top
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5 did nothing
dual agonist, GIP as well as GLP-1, thats the whole difference in one line
sorry to jump in the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
the trials titrated every four weeks to a target, most people here stop at whatever works
New independent result logged — KP, lot A-2418, purity 99.4% (PeptideMeter).
5 was where i first noticed it properly, 2.5 did almost nothing for me
[edited]i argued the sweet spot was nonsense and then spent 24 months at 7.5 not needing more
genuine question the switch felt like a step down at first and then caught up around week 5, thats one data point
same plateau here
[edited]start low anyway
checked the units twice
🙏12
no gap when i switched, took the last semaglutide dose and started this a week later, from memory
went back to semaglutide after 13 months because the cost difference mattered more than the GI, thats one data point
SURMOUNT-1 versus SURPASS-2, which one was the weight trial
switched last year
for the archive there is no clean conversion between the two, anyone giving you a ratio is guessing, we shall see
coming off semaglutide, is there a conversion or do i restart at 2.5
for the archive why does everyone talk about 7.5 and not 10
12 did nothing extra over 10 for me and that still holds a year later, for what its worth
did anyone find the GI easier than semaglutide at an equivalent effect
at 0.5 my appetite went completely and i dropped back a step, eating nothing isnt a win
if youre coming off semaglutide the honest answer is start low and find out, theres no table
👍7📈12✅11
the 2.5 to 5 step was the roughest one for me and everything after was easier
anyone got a 4 recon they like for the 15 vials
does the GIP arm actually explain the easier nausea or is that hand waving
did anybody switch back to semaglutide after trying this
switched from 1.7 semaglutide and started at 2.5, took the slow route, never regretted it
back after 4 months, do i restart at 2.5 or pick up near where i left off
whats the plateau pattern here, same as semaglutide or different
at 2.4 my appetite is gone entirely, did anyone go down rather than up
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)