how many weeks at 7.5 before you knew it was enough
#tirzepatide 2024-12-07
Saturday39 messages7 participantstimes are UTC
Highlights from this day
- truncation_tru — genuine question at 0.5 my appetite is gone entirely, did anyone go down rather than up 18:33
- reta_resting_hr — SURMOUNT-1 versus SURPASS-2, which one was the weight trial 18:52
- truncation_tru — is the sweet spot argument about effect or about side effects 19:12
- nhs_pathway_nell — at 0.5 my appetite went completely and i dropped back a step, eating nothing isnt a win 19:36
- truncation_tru — the 2.5 to 5 step was the roughest one for me and everything after was easier 20:26
genuine question at 0.5 my appetite is gone entirely, did anyone go down rather than up
did anybody switch back to semaglutide after trying this
did going from 2.5 semaglutide to 5 of this feel like a step down for anyone
SURMOUNT-1 versus SURPASS-2, which one was the weight trial
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5 was where i first noticed it properly, 2.5 did almost nothing for me
anyone got a 2.5 recon they like for the 20 vials
did anyone find the GI easier than semaglutide at an equivalent effect
is the sweet spot argument about effect or about side effects
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whats the top licensed dose, 15 or does it go higher
dual agonist, GIP as well as GLP-1, thats the whole difference in one line
checked the units twice
why does everyone talk about 7.5 and not 10
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went back to semaglutide after 4 months because the cost difference mattered more than the GI
at 0.5 my appetite went completely and i dropped back a step, eating nothing isnt a win
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does switching from semaglutide need a gap or do you just start
if youre coming off semaglutide the honest answer is start low and find out, theres no table
SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted
15 is the top
truncation_trugenuine question at 0.5 my appetite is gone entirely, did anyone go down rather than up
is 7.5 really the sweet spot or is that just channel folklore
did anyone go past 15 and was there any point to it
the 2.5 to 5 step was the roughest one for me and everything after was easier
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folklore probably
[edited]easier gi for me
for the archive is the 10 vial the common one or do people use 40
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quick one does the GIP arm actually explain the easier nausea or is that hand waving
for the archive GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
is SURMOUNT-OSA the sleep apnoea one
im at 1.7 and thinking about 0.25, did anyone gain anything from that step
i sat at 7.5 for 12 months and never needed more, which is where the folklore comes from, i think
7.5 gang
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)the GI difference held for me right up to 15, which isnt what a couple of people here found
5 did nothing
ok so the 30 vial in 1ml gives 4mg/ml which puts 0.25 on 40 units, nice round numbers
the trials titrated every four weeks to a target, most people here stop at whatever works
no clean conversion
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reta_resting_hrthe GI difference held for me right up to 15, which isnt what a couple of people here…
coming off semaglutide, is there a conversion or do i restart at 2.5
SURMOUNT is weight
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quick one the sweet spot thing is survivorship, the people it worked for stayed and said so