the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in
#storage-coldchain 2026-06-03
- taper_or_not — genuine question does anyone freeze reconstituted vials or is that madness 14:42
- taper_or_not — i have never had a lyophilised vial fail after a warm transit and i have had some bad ones 14:57
- noct.titrate — update on the earlier thing lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear 15:01
- pbs_pip — genuine question update from 9 months ago: replaced the fridge, temperature is stable, no more anxiety 17:42
- vale_vials — a liquid cold pack tells you it was above freezing, not that your vial cooked 17:55
power cut for 4 hours, fridge stayed shut, am i fine
anyone tested a vial before and after a bad transit
unopened and in-use in the same place is fine. just keep the in-use one where you can reach it
do you log the fridge temperature or is that too far
genuine question does anyone freeze reconstituted vials or is that madness
buy a thermometer. mine reads 3.1 on the door and two degrees lower at the back, anyway
i have never had a lyophilised vial fail after a warm transit and i have had some bad ones
right so do you keep the unopened vials and the in-use one in the same place
update on the earlier thing lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear
mon 4.1 / door 7.2
tue 4.0 / door 7.8
wed 4.2 / door 6.9
thu 3.9 / door 7.4
fri 4.1 / door 8.1 <- shopping day
sat 4.3 / door 7.0
sun 4.0 / door 6.8for the archive does the fridge in a hotel room count as a fridge
light exposure matters much less than temperature for these. i still keep them in the carton
two to eight degrees. most domestic fridge doors are not in that range and people do not check
if you are worried after a bad transit, test it. that is what the testing channels are for
a cooler with two gel packs held under eight degrees for eleven hours on a drive
genuine question update from 9 months ago: replaced the fridge, temperature is stable, no more anxiety
a few hours at room temperature is almost certainly nothing. a week is a different conversation
*week 19 not week 4
log it
i would bin it
a liquid cold pack tells you it was above freezing, not that your vial cooked