vialroom

#storage-coldchain 2026-05-31

Sunday45 messages8 participantstimes are UTC
Highlights from this day
  • cold_chain_cmdr — i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine 11:27
  • net_peptide — how long is reconstituted actually good for at room temperature 12:51
  • tenpence — unrelated but does anyone freeze reconstituted vials or is that madness 15:30
  • tenpence — update from 24 months ago: replaced the fridge, temperature is stable, no more anxiety, ask me again in a month 16:41
NP

ok so i keep everything at the back of the middle shelf, never the door, ask me again in a month

do you log the fridge temperature or is that too far

VO

a liquid cold pack tells you it was above freezing, not that your vial cooked

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what temperature does a domestic fridge door actually swing to

quick one the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in

do i need to worry about light exposure or is that overthinking

VB

Testing queue: 2 submissions open, 11 awaiting dispatch.

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PP

a few hours at room temperature is almost certainly nothing. a week is a different conversation, ask me again in a month

PP

ok so the door swings four or five degrees every time somebody opens it. the back barely moves

CC

i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine

[edited]
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PP

genuine question lyophilised at room temp for 4 days in transit, worried or not

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VO

reconstituted solution is the fragile part. that is where the cold chain actually earns its keep

NP

freeze thaw cycling is the risk, not one freeze. that is my read of it anyway

how long is reconstituted actually good for at room temperature

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hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct

if you are worried after a bad transit, test it. that is what the testing channels are for

13:16tenpence pinned a message

i have never had a lyophilised vial fail after a warm transit and i have had some bad ones

TE

does the fridge in a hotel room count as a fridge

buy a thermometer. mine reads 3.1 on the door and two degrees lower at the back

TE

unrelated but does anyone freeze reconstituted vials or is that madness

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TE

unopened and in-use in the same place is fine. just keep the in-use one where you can reach it

parcel sat in a hot mailbox for 5 hours, is it dead

16:34tenpence pinned a message to this channel

the vial that visibly changed after a warm transit was the one that had already been reconstituted

update on the earlier thing anyone tested a vial before and after a bad transit

update from 24 months ago: replaced the fridge, temperature is stable, no more anxiety, ask me again in a month

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NP

how cold is too cold, can it actually freeze in a normal fridge