is a five pound fridge thermometer actually worth it
#storage-coldchain 2025-05-26
Monday21 messages6 participantstimes are UTC
Highlights from this day
- VialBot — Recon calculator: 5mg in 0.5ml = 2.5mg/ml. 08:21
- nhs_pathway_nell — do you log the fridge temperature or is that too far 08:23
- auckland_aliquot — a cooler with two gel packs held under eight degrees for eleven hours on a drive 09:48
- stack_sceptic — the vial that visibly changed after a warm transit was the one that had already been reconstituted 11:45
back of the fridge
🔥5
gel packs
Recon calculator: 5mg in 0.5ml = 2.5mg/ml.
do you log the fridge temperature or is that too far
mon 4.1 / door 7.2
tue 4.0 / door 7.8
wed 4.2 / door 6.9
thu 3.9 / door 7.4
fri 4.1 / door 8.1 <- shopping day
sat 4.3 / door 7.0
sun 4.0 / door 6.8📉6🧊9🙏5
lyophilised at room temp for 11 days in transit, worried or not
a few hours at room temperature is almost certainly nothing. a week is a different conversation
light exposure matters much less than temperature for these. i still keep them in the carton, n of 1 obviously
ok so the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in
i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine
best travel setup for 19 days away with vials
while im here unopened and in-use in the same place is fine. just keep the in-use one where you can reach it
a cooler with two gel packs held under eight degrees for eleven hours on a drive
i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why
i have never had a lyophilised vial fail after a warm transit and i have had some bad ones
if you are worried after a bad transit, test it. that is what the testing channels are for
two to eight degrees. most domestic fridge doors are not in that range and people do not check
test it
[edited]the vial that visibly changed after a warm transit was the one that had already been reconstituted
💀8🧊8👍3
power cut with the door shut for a few hours is fine. a full fridge holds temperature surprisingly well, we shall see
not the door