vialroom

#storage-coldchain 2025-02-22

Saturday29 messages6 participantstimes are UTC
Highlights from this day
  • VialBot — Assay note: WXT lot D-0718 reported at 98.1% of label content. 22:48
  • deamidation — freeze thaw cycling is the risk, not one freeze. that is my read of it anyway 23:43
  • deamidation — while im here a liquid cold pack tells you it was above freezing, not that your vial cooked 23:58
DE

how long is reconstituted actually good for at room temperature

VV

i keep everything at the back of the middle shelf, never the door

RT

i have never had a lyophilised vial fail after a warm transit and i have had some bad ones

VB

Assay note: WXT lot D-0718 reported at 98.1% of label content.

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VV

a cooler with two gel packs held under eight degrees for eleven hours on a drive

[edited]

anyone had a vial visibly change after a warm transit

[edited]

follow up update from 9 months ago: replaced the fridge, temperature is stable, no more anxiety

update on the earlier thing coming back after 26 months, is the pinned storage table still current

the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in, n of 1 obviously

unopened and in-use in the same place is fine. just keep the in-use one where you can reach it

the vial that visibly changed after a warm transit was the one that had already been reconstituted

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log it

do i need to worry about light exposure or is that overthinking

freeze debate again

test it

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DE

i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine

DD

slightly off topic but i log the fridge temperature daily and the room has never let me forget it

cold pack arrived completely liquid, does that mean anything

VB

On this day 7 years ago this channel logged 112 messages.

DE

freeze thaw cycling is the risk, not one freeze. that is my read of it anyway

fridge-temps.csv
485 rows · not retained in the public archive
DE

while im here a liquid cold pack tells you it was above freezing, not that your vial cooked

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