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#side-effects 2024-09-04

Wednesday47 messages10 participantstimes are UTC
Highlights from this day
  • VialBot — archive lookup: telogen effluvium — 34 matches in #side-effects, earliest 2024-03-11. most-read: shedding at month 3 and what actually helped 21:20
  • HPLC_Hank — it does appear in the trial tables at low rates, and it tracks with how much weight came off 21:36
  • HPLC_Hank — if you are getting bloods done, stop biotin well before the draw and tell whoever ordered it 22:32
LN

let the alcohol dry before you inject. that alone fixes a lot of the stinging

update on the earlier thing if you are under 1000 calories by accident that is a problem, not discipline
the dose day matters more than the dose for the GI stuff, at least for me

sorry youre having a rough one

SS

taste changes settled for me around week eight and never fully came back

LN

eating small and often was the only thing that made the first month liveable for me

SS

dropping back a rung for a fortnight is a completely legitimate move

🤝1

that settles

FM

month 3 and my hair is coming out in the shower. is this the drug

HH

telogen effluvium. a stress event pushes a chunk of follicles into the shedding phase together, and you see it two to four months later

so if you started losing fast in month 1, month 3 to 4 is exactly when you would notice

HH

in the usual case it is self limiting. the follicles are not dead, they all restarted the cycle at once

TT

mine took about four months from the peak shed to looking normal again

VB

archive lookup: telogen effluvium — 34 matches in #side-effects, earliest 2024-03-11. most-read: shedding at month 3 and what actually helped

HH

it does appear in the trial tables at low rates, and it tracks with how much weight came off

Cited study
Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1)
New England Journal of Medicine · 2022
alopecia is listed among the uncommon adverse events, reported more at higher doses and with greater weight loss
HH

that is the inference most people draw. the trial was not designed to answer it

TT

the practical levers are rate of loss, protein, and iron status. all three are things you can actually check

HH

ferritin and B12 both slide when intake drops. worth knowing your numbers before you start guessing

VV

mine was ferritin. sorted that and the shed stopped a couple of months later

6
HH

biotin will not fix a shed you caused with a calorie deficit. it will however interfere with some thyroid and troponin assays

if you are getting bloods done, stop biotin well before the draw and tell whoever ordered it

⚠️11
22:35vacuum_vic pinned a message
FM

slowed down. dropped back a dose and stopped chasing the scale

FM

eight weeks before the shower stopped being horrifying. not fast