vialroom

#semaglutide 2026-06-20

Saturday19 messages5 participantstimes are UTC
Highlights from this day
  • bea_reconstitutes — half life is about a week so youre roughly four to five weeks to steady state on any new dose 14:40
  • bea_reconstitutes — lost about 25kg on the low doses before i even got to 1, which surprised me going slow cost me nothing except time and saved me two bad weeks, thats my whole… 14:58
  • coa_or_cope — my Medutest report on the Homopeptide vial came back 99 against a certificate saying 96.8 16:10
SS

changed my mind on the four week rule, i think it depends entirely on how the current dose feels

BR

half life is about a week so youre roughly four to five weeks to steady state on any new dose

💀16

FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure

SS

my dose day drifted from friday to sunday, does that reset anything
24 months at 2.4 and the honest summary is diminishing returns after the first half

STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping

BR

lost about 25kg on the low doses before i even got to 1, which surprised me
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution

ST

steady state is the bit people skip, judging a new dose after eight days tells you almost nothing, for what its worth

SB

the plateau hit me at 23 weeks and moved again about a month later without a dose change

BR

the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing, ymmv

STEP 1 ran to 68 weeks. thats the one everyone half remembers

CO

my Medutest report on the Homopeptide vial came back 99 against a certificate saying 96.8

ST

sorry to jump in i stayed on 1.7 for 19 months and never went to 2.4, appetite was already where i needed it, from memory

CO

restarted after 14 months off at a low dose and the nausea arrived exactly like the first time

CO

how long till steady state, ive read the half life is about a week