i stayed on 1.7 for 6 months and never went to 2.4, appetite was already where i needed it
#semaglutide 2026-05-31
Sunday54 messages9 participantstimes are UTC
Highlights from this day
- panel_before_after — STEP is several trials, so saying STEP said x is usually wrong without a number after it 13:52
- gip_glp_gil — i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication 14:04
- osier_orders — my Janoshik report on the CPC vial came back 98.6 against a certificate saying 99.4 16:01
- motivation_gone — does the licensed ceiling for weight differ from the diabetes one 16:03
- motivation_gone — update on the earlier thing is there a reason to hold at 1.7 rather than going to 2.4 16:43
STEP is several trials, so saying STEP said x is usually wrong without a number after it
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update on the earlier thing did the STEP 4 withdrawal arm show what i think it showed
i stayed on 1.7 for 17 months and never went to 2.4, appetite was already where i needed it
changed my mind on the four week rule, i think it depends entirely on how the current dose feels
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
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same dose day
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seven days ish
the appetite effect faded for me around 16 months and going up fixed it for a while
SELECT wasnt weight
moving my dose day by a day or two never did anything noticeable for me
the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing
went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step
steady state is the bit people skip, judging a new dose after eight days tells you almost nothing
is the plateau at 13 weeks normal or am i doing something wrong
mine faded too
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lost about 47kg on the low doses before i even got to 1, which surprised me
held at 1 and lost 28lb over 3 months, slower than the trials and fine by me
what did SELECT actually measure, i see it quoted for everything
restarted after 22 months off at a low dose and the nausea arrived exactly like the first time
back after 4 months off, do i restart at 0.25 or somewhere higher
my 30 vial in 2ml gives 2.5mg/ml so 2.5 lands on 8 units, thats why i picked that volume
my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
how long till steady state, ive read the half life is about a week
give it four weeks
im 7 months in at 15 and the appetite effect faded, is that a thing
steady state takes weeks
five week steps worked better for me than four, purely on how the second week felt
dose day is sunday for me only because thats when i remember, not because sunday matters
my Janoshik report on the CPC vial came back 98.6 against a certificate saying 99.4
does the licensed ceiling for weight differ from the diabetes one
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nausea_windowthe trials titrated on a fixed schedule, most people here dont, worth remembering when…
is the plateau usually appetite coming back or just the scale stopping
licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose
follow up the plateau hit me at 23 weeks and moved again about a month later without a dose change
unrelated but is 2.4 the top or do people go past it
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
update on the earlier thing is there a reason to hold at 1.7 rather than going to 2.4
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how did people handle the jump from 1 to 1.7
plateaus move
went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down
does moving my dose day by two days matter with a seven day half life
FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
does anyone actually run a five week step instead of four
how long did the first 41kg take for people at the low doses
quick one $38 a month for compounded against what brand costs locally is why most people here use vials, ask me again in a month
not the same trial
compounded and brand felt the same to me at 1, which is one person and nothing more
[edited]went too fast once
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how many weeks before you noticed anything at 1
brand vs compounded, is there a difference people can actually feel
anyone gone from 2 straight to 12 or is that too big a jump
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule, i could be wrong
my dose day drifted from friday to sunday, does that reset anything
vials not pens here