how long till steady state, ive read the half life is about a week
#semaglutide 2026-04-10
Friday26 messages6 participantstimes are UTC
Highlights from this day
- cold_start_cy — back after 17 months off, do i restart at 0.25 or somewhere higher went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step 13:57
- cold_start_cy — lost about 5kg on the low doses before i even got to 1, which surprised me 14:31
- cold_start_cy — going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution 15:20
held at 7.5 and lost 82lb over 15 months, slower than the trials and fine by me
steady state is the bit people skip, judging a new dose after eight days tells you almost nothing
went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down
my PeptideMeter report on the GGPeps vial came back 99.4 against a certificate saying 98.6
slightly off topic but dose day is sunday for me only because thats when i remember, not because sunday matters
is the plateau at 3 weeks normal or am i doing something wrong
[edited]STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping
the appetite effect faded for me around 21 months and going up fixed it for a while
back after 17 months off, do i restart at 0.25 or somewhere higher
went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step
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did anybody find a difference between SSA and pharmacy at the same 0.5
SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
16 months at 2.4 and the honest summary is diminishing returns after the first half
lost about 5kg on the low doses before i even got to 1, which surprised me
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did anyone titrate slower than four weeks a step and how did that go
my dose day drifted from friday to sunday, does that reset anything
vials not pens here
Archive lookup: travel_cooler first appears in this channel on 2025-10-11.
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going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
wk 1-4 0.25mg
wk 5-10 0.50mg (held 2 extra weeks)
wk 11-14 1.00mg
wk 15-26 1.70mg (held, long)
wk 27+ 2.40mgcompounded and brand felt the same to me at 0.25, which is one person and nothing more
2 months at 2.4 and the honest summary is diminishing returns after the first half
held there too
five week steps worked better for me than four, purely on how the second week felt
give it four weeks
follow up licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose, ymmv
anyone compared their 5 vial dosing against the pen increments