i dont think the plateau is a dose problem most of the time, but i cant prove that
#semaglutide 2026-04-01
Wednesday25 messages4 participantstimes are UTC
Highlights from this day
- yyz_vial — $55 a month for compounded against what brand costs locally is why most people here use vials, ill dig out the number 18:31
- reading_the_pins — the long half life flattens the trough more than people expect, i never felt a day seven dip 18:38
- reading_the_pins — changed my mind on the four week rule, i think it depends entirely on how the current dose feels 19:47
- yyz_vial — sorry to jump in went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step, thats just me 21:25
- seizure_letter — dose day is sunday for me only because thats when i remember, not because sunday matters if youre comparing brand to compounded, dose accuracy in the vial is the… 21:30
STEP 1 ran to 68 weeks. thats the one everyone half remembers
the appetite effect faded for me around 6 months and going up fixed it for a while
$55 a month for compounded against what brand costs locally is why most people here use vials, ill dig out the number
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
seven days ish
steady state is the bit people skip, judging a new dose after eight days tells you almost nothing
slightly off topic but im at 0.5 and stuck, did anyone break a plateau without going up
five week steps worked better for me than four, purely on how the second week felt
licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose
the long half life flattens the trough more than people expect, i never felt a day seven dip
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how long till steady state, ive read the half life is about a week
restarted after 12 months off at a low dose and the nausea arrived exactly like the first time, anyway
steady state takes weeks
*week 9 not week 4
mine faded too
held there too
brand vs compounded, is there a difference people can actually feel
FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
anyone compared their 10 vial dosing against the pen increments
changed my mind on the four week rule, i think it depends entirely on how the current dose feels
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i stayed on 1.7 for 12 months and never went to 2.4, appetite was already where i needed it
went too fast once
sorry to jump in went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step, thats just me
dose day is sunday for me only because thats when i remember, not because sunday matters
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule