seven days ish
#semaglutide 2026-02-11
Wednesday32 messages6 participantstimes are UTC
Highlights from this day
- red_flag_ruby — did anybody find a difference between SSA and pharmacy at the same 0.25 16:50
- lisbon_lot — back after 24 months off, do i restart at 0.25 or somewhere higher 17:30
- provincial_pat — does anyone actually run a five week step instead of four 18:20
- provincial_pat — how many weeks before you noticed anything at 1.7 19:07
im at 15 and stuck, did anyone break a plateau without going up
the plateau hit me at 26 weeks and moved again about a month later without a dose change
brand vs compounded, is there a difference people can actually feel
FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
same dose day
steady state takes weeks
vial units and pen clicks are different systems, mixing the two is how people end up wrong
did anybody find a difference between SSA and pharmacy at the same 0.25
went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down
my Medutest report on the FGP vial came back 98.6 against a certificate saying 99.4
lost about 28kg on the low doses before i even got to 1, which surprised me, n of 1 obviously
[edited]i dont think the plateau is a dose problem most of the time, but i cant prove that
back after 24 months off, do i restart at 0.25 or somewhere higher
🎉1⚠️5👀15
quick one does the licensed ceiling for weight differ from the diabetes one
was SURPASS-2 the one that ran to 68 weeks or am i mixing them up
🧪2
SELECT wasnt weight
how long till steady state, ive read the half life is about a week
does the seven day half life mean the last two days are weaker
does anyone actually run a five week step instead of four
👍1😂15📈18
went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
🧊2
licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
how long did the first 15kg take for people at the low doses
$38 a month for compounded against what brand costs locally is why most people here use vials
how many weeks before you noticed anything at 1.7
dose day is sunday for me only because thats when i remember, not because sunday matters
is the plateau at 6 weeks normal or am i doing something wrong
vials not pens here
moving my dose day by a day or two never did anything noticeable for me
did anyone hold at 2 longer than four weeks before going up
not the same trial
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |