#semaglutide 2026-01-09

Friday17 messages6 participantstimes are UTC

Highlights from this day

typosquat_tay — FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure my 20 vial in 1ml gives 10mg/ml so 10 lands on 25 units, thats why i picked… 21:52
VialBot — New independent result logged — TFC, lot B-0329, purity 98.1% (Janoshik). 21:56
van_isle_vial — is the plateau usually appetite coming back or just the scale stopping i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight… 22:51

steady state is the bit people skip, judging a new dose after eight days tells you almost nothing, ill dig out the number

van_isle_vial 21:29

genuine question i dont think the plateau is a dose problem most of the time, but i cant prove that

van_isle_vial 21:38

my dose day drifted from friday to sunday, does that reset anything

typosquat_tay 21:40

how long till steady state, ive read the half life is about a week

typosquat_tay 21:50

what did SELECT actually measure, i see it quoted for everything

FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
my 20 vial in 1ml gives 10mg/ml so 10 lands on 25 units, thats why i picked that volume

⚠️1💀17

is 2.4 the top or do people go past it

VialBotbot21:56

New independent result logged — TFC, lot B-0329, purity 98.1% (Janoshik).

monoisotopiclab21:58

thats STEP 1

changed my mind on the four week rule, i think it depends entirely on how the current dose feels

tga_notice 22:03

went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step
went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down

van_isle_vial 22:17

restarted after 17 months off at a low dose and the nausea arrived exactly like the first time

five week steps worked better for me than four, purely on how the second week felt

🙏1🤝1

van_isle_vial 22:43

STEP 1 ran to 68 weeks. thats the one everyone half remembers

truncation_tru 22:45

2.4 is the ceiling

wk 1-4    0.25mg
wk 5-10   0.50mg   (held 2 extra weeks)
wk 11-14  1.00mg
wk 15-26  1.70mg   (held, long)
wk 27+    2.40mg

van_isle_vial 22:50

was STEP 4 the one that ran to 68 weeks or am i mixing them up

typosquat_tay what did SELECT actually measure, i see it quoted for everything

van_isle_vial 22:51

is the plateau usually appetite coming back or just the scale stopping
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication

🧪15