mine faded too
#semaglutide 2025-11-25
Tuesday36 messages9 participantstimes are UTC
Highlights from this day
- see_a_clinician — was STEP 4 the one that ran to 68 weeks or am i mixing them up 06:26
- maintenance_mo — the plateau hit me at 6 weeks and moved again about a month later without a dose change if youre comparing brand to compounded, dose accuracy in the vial is the… 08:57
- vale_vials — i dont think the plateau is a dose problem most of the time, but i cant prove that 10:06
- maintenance_mo — half life is about a week so youre roughly four to five weeks to steady state on any new dose 11:15
was STEP 4 the one that ran to 68 weeks or am i mixing them up
give it four weeks
slightly off topic but does moving my dose day by two days matter with a seven day half life
five week steps worked better for me than four, purely on how the second week felt
went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down
SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
anyone compared their 8 vial dosing against the pen increments
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
my 2 vial in 1ml gives 2.5mg/ml so 2.4 lands on 30 units, thats why i picked that volume
STEP is several trials, so saying STEP said x is usually wrong without a number after it
2.4 is the ceiling
the appetite effect faded for me around 22 months and going up fixed it for a while
SELECT wasnt weight
not the same trial
did anyone titrate slower than four weeks a step and how did that go
update on the earlier thing is 2.4 the top or do people go past it
is the plateau at 31 weeks normal or am i doing something wrong
*Medutest not the other one
vials not pens here
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update on the earlier thing licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose, thats just me
did the STEP 4 withdrawal arm show what i think it showed
brand vs compounded, is there a difference people can actually feel
what did SELECT actually measure, i see it quoted for everything
sorry to jump in held at 2.5 and lost 86lb over 14 months, slower than the trials and fine by me
Inter-lab diff for lot C-4402: 99.4% vs 98.6%. Within expected range.
the plateau hit me at 6 weeks and moved again about a month later without a dose change
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
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how long till steady state, ive read the half life is about a week
[edited]does the seven day half life mean the last two days are weaker
On this day 9 years ago this channel logged 120 messages.
i dont think the plateau is a dose problem most of the time, but i cant prove that
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is the plateau usually appetite coming back or just the scale stopping
lost about 16kg on the low doses before i even got to 1, which surprised me
dose day is sunday for me only because thats when i remember, not because sunday matters
for the archive STEP 1 ran to 68 weeks. thats the one everyone half remembers, thats one data point
went too fast once
vial units and pen clicks are different systems, mixing the two is how people end up wrong, i could be wrong
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half life is about a week so youre roughly four to five weeks to steady state on any new dose
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