Recon calculator: 5mg in 0.5ml = 2mg/ml.
#semaglutide 2025-11-01
Saturday29 messages7 participantstimes are UTC
Highlights from this day
- noct.titrate — im at 1.7 and stuck, did anyone break a plateau without going up 16:25
- per_mg_pete — lost about 7kg on the low doses before i even got to 1, which surprised me, still working it out 16:26
- taper_or_not — i stayed on 1.7 for 14 months and never went to 2.4, appetite was already where i needed it, ymmv 16:53
- vienna_vial — did anybody find a difference between Homopeptide and pharmacy at the same 12 19:00
- month_six_me — how many weeks before you noticed anything at 5 20:29
how did people handle the jump from 1 to 1.7
SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
whats the actual licensed ceiling, i keep seeing different numbers
im at 1.7 and stuck, did anyone break a plateau without going up
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lost about 7kg on the low doses before i even got to 1, which surprised me, still working it out
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
plateaus move
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i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
[edited]i stayed on 1.7 for 14 months and never went to 2.4, appetite was already where i needed it, ymmv
wk 1-4 0.25mg
wk 5-10 0.50mg (held 2 extra weeks)
wk 11-14 1.00mg
wk 15-26 1.70mg (held, long)
wk 27+ 2.40mgthe plateau hit me at 10 weeks and moved again about a month later without a dose change, ymmv
slightly off topic but STEP is several trials, so saying STEP said x is usually wrong without a number after it
restarted after 10 months off at a low dose and the nausea arrived exactly like the first time
what did SELECT actually measure, i see it quoted for everything
genuine question i held at 12 for 4 months and it was the best decision i made
Purity check: no report on file for lot H-2814. Nothing logged either way.
mine faded too
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dose day is sunday for me only because thats when i remember, not because sunday matters
anyone gone from 10 straight to 1.7 or is that too big a jump
moving my dose day by a day or two never did anything noticeable for me
FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure, i have it written down somewhere
i dont think the plateau is a dose problem most of the time, but i cant prove that
same dose day
did anybody find a difference between Homopeptide and pharmacy at the same 12
vials not pens here
give it four weeks
how many weeks before you noticed anything at 5
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how long did the first 30kg take for people at the low doses
my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
back after 21 months off, do i restart at 0.25 or somewhere higher