did anybody find a difference between WWB and pharmacy at the same 0.25
#semaglutide 2025-07-10
Thursday39 messages9 participantstimes are UTC
Highlights from this day
- pin29g — did anybody find a difference between WWB and pharmacy at the same 0.25 11:11
- reta_resting_hr — sorry to jump in steady state is the bit people skip, judging a new dose after eight days tells you almost nothing 11:17
- pin29g — does the licensed ceiling for weight differ from the diabetes one 18:10
vials not pens here
im 23 months in at 1.7 and the appetite effect faded, is that a thing
👀5
give it four weeks
sorry to jump in steady state is the bit people skip, judging a new dose after eight days tells you almost nothing
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
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anyone gone from 15 straight to 1.7 or is that too big a jump
Digest for the week of 2025-04-07 has been published.
i stayed on 1.7 for 7 months and never went to 2.4, appetite was already where i needed it
held at 5 and lost 36lb over 14 months, slower than the trials and fine by me
same dose day
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changed my mind on the four week rule, i think it depends entirely on how the current dose feels
On this day 8 years ago this channel logged 25 messages.
mine faded too
went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step
vial units and pen clicks are different systems, mixing the two is how people end up wrong
licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose
thats STEP 1
weights-monthly.csv
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😂11👀6❤️2
my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
moving my dose day by a day or two never did anything noticeable for me
did anyone titrate slower than four weeks a step and how did that go
held at 0.5 and lost 30lb over 3 months, slower than the trials and fine by me
my dose day drifted from friday to sunday, does that reset anything
2.4 is the ceiling
ok so is there a reason to hold at 1.7 rather than going to 2.4
did anyone hold at 15 longer than four weeks before going up
how long till steady state, ive read the half life is about a week
seven days ish
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i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping
does anyone actually run a five week step instead of four
how long did the first 25kg take for people at the low doses
i dont think the plateau is a dose problem most of the time, but i cant prove that
STEP 1 ran to 68 weeks. thats the one everyone half remembers, not advice obviously
the long half life flattens the trough more than people expect, i never felt a day seven dip, i think
*Medutest not the other one
does the licensed ceiling for weight differ from the diabetes one
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slower worked better
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
plateaus move
STEP is several trials, so saying STEP said x is usually wrong without a number after it
ok so anyone compared their 2 vial dosing against the pen increments