my 40 vial in 2ml gives 10mg/ml so 12 lands on 10 units, thats why i picked that volume
#semaglutide 2025-07-01
Tuesday50 messages11 participantstimes are UTC
Highlights from this day
- VialBot — Channel stats, last 30 days: 105 messages from 22 members. 14:37
- split_the_cost — sorry to jump in my plateau was the scale stopping while appetite stayed suppressed, which is a different problem my 2 vial in 5ml gives 8mg/ml so 2.4 lands on 12… 14:48
- cagri_curious — changed my mind on the four week rule, i think it depends entirely on how the current dose feels went to 2.4 and the extra suppression wasnt worth the GI for me, so i… 16:15
- still_here_2024 — 14 months at 2.4 and the honest summary is diminishing returns after the first half, thats one data point 17:58
did the STEP 4 withdrawal arm show what i think it showed
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same dose day
Channel stats, last 30 days: 105 messages from 22 members.
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sorry to jump in my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
my 2 vial in 5ml gives 8mg/ml so 2.4 lands on 12 units, thats why i picked that volume
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i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
dose day is sunday for me only because thats when i remember, not because sunday matters
SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
brand vs compounded, is there a difference people can actually feel
the appetite effect faded for me around 26 months and going up fixed it for a while, thats just me
how did people handle the jump from 1 to 1.7
steady state is the bit people skip, judging a new dose after eight days tells you almost nothing
how many weeks before you noticed anything at 5
new_here_natdose day is sunday for me only because thats when i remember, not because sunday matters
FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure, ill dig out the number
does the seven day half life mean the last two days are weaker
janoshik-c-4402.pdf
2 pages · 478 KB · not retained in the public archive
does the licensed ceiling for weight differ from the diabetes one
changed my mind on the four week rule, i think it depends entirely on how the current dose feels
went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down
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the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing
went too fast once
was SURMOUNT-OSA the one that ran to 68 weeks or am i mixing them up
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
vial units and pen clicks are different systems, mixing the two is how people end up wrong
restarted after 8 months off at a low dose and the nausea arrived exactly like the first time
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STEP is several trials, so saying STEP said x is usually wrong without a number after it
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seven days ish
im at 12 and stuck, did anyone break a plateau without going up
steady state takes weeks
wk 1-4 0.25mg
wk 5-10 0.50mg (held 2 extra weeks)
wk 11-14 1.00mg
wk 15-26 1.70mg (held, long)
wk 27+ 2.40mgwent to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
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how long till steady state, ive read the half life is about a week
what did SELECT actually measure, i see it quoted for everything
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SELECT wasnt weight
is the plateau usually appetite coming back or just the scale stopping
split_the_costSTEP is several trials, so saying STEP said x is usually wrong without a number after it
14 months at 2.4 and the honest summary is diminishing returns after the first half, thats one data point
wk 1-4 0.25mg
wk 5-10 0.50mg (held 2 extra weeks)
wk 11-14 1.00mg
wk 15-26 1.70mg (held, long)
wk 27+ 2.40mg🙏1😂1🧪18
not the same trial
did anybody find a difference between CPC and pharmacy at the same 7.5
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is there a reason to hold at 1.7 rather than going to 2.4
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follow up STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping
slower worked better
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule, take that with a pinch of salt
mine faded too
moving my dose day by a day or two never did anything noticeable for me
thats STEP 1
my dose day drifted from friday to sunday, does that reset anything
Reminder set. I will post here in 4 days.
give it four weeks
whats the actual licensed ceiling, i keep seeing different numbers
plateaus move
is 2.4 the top or do people go past it
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five week steps worked better for me than four, purely on how the second week felt
anyone compared their 10 vial dosing against the pen increments