same dose day
#semaglutide 2025-05-16
Friday46 messages11 participantstimes are UTC
Highlights from this day
- is_this_forever — 6 months at 2.4 and the honest summary is diminishing returns after the first half 19:44
- VialBot — Assay note: ERP lot E-2205 reported at 99.2% of label content. 20:47
- split_dose_sam — $55 a month for compounded against what brand costs locally is why most people here use vials, i have it written down somewhere i dont think the plateau is a dose… 21:19
- night_pin — licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose 22:01
plateaus move
slower worked better
On this day 2 years ago this channel logged 34 messages.
FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
steady state is the bit people skip, judging a new dose after eight days tells you almost nothing
five week steps worked better for me than four, purely on how the second week felt
🧪5
*week 19 not week 4
6 months at 2.4 and the honest summary is diminishing returns after the first half
⚠️11📉3👀1
compounded and brand felt the same to me at 2, which is one person and nothing more, i think
the plateau hit me at 3 weeks and moved again about a month later without a dose change
🧪4
i stayed on 1.7 for 12 months and never went to 2.4, appetite was already where i needed it
not the same trial
was SURMOUNT-OSA the one that ran to 68 weeks or am i mixing them up
my dose day drifted from friday to sunday, does that reset anything
held there too
steady state takes weeks
SELECT wasnt weight
changed my mind on the four week rule, i think it depends entirely on how the current dose feels
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
thats STEP 1
my Medutest report on the TFC vial came back 99.4 against a certificate saying 99.2
back after 10 months off, do i restart at 0.25 or somewhere higher
👀8📉1
2.4 is the ceiling
❤️15👀12🙏1
genuine question held at 10 and lost 49lb over 6 months, slower than the trials and fine by me, i have it written down somewhere
i held at 0.5 for 4 months and it was the best decision i made
SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
Testing queue: 9 submissions open, 65 awaiting dispatch.
Assay note: ERP lot E-2205 reported at 99.2% of label content.
Assay note: MKM lot H-2814 reported at 98.1% of label content.
does moving my dose day by two days matter with a seven day half life
dose day is sunday for me only because thats when i remember, not because sunday matters
$55 a month for compounded against what brand costs locally is why most people here use vials, i have it written down somewhere
i dont think the plateau is a dose problem most of the time, but i cant prove that
📈1🧪10
went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down
the long half life flattens the trough more than people expect, i never felt a day seven dip
vial units and pen clicks are different systems, mixing the two is how people end up wrong
🤝8🔥1
*VendorInvestigate not the other one
im 15 months in at 5 and the appetite effect faded, is that a thing
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose
✅7👀8🎉2
lost about 21kg on the low doses before i even got to 1, which surprised me
moving my dose day by a day or two never did anything noticeable for me
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
coming back to this im at 0.5 and stuck, did anyone break a plateau without going up
my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule