vials not pens here
#semaglutide 2025-04-22
Tuesday47 messages9 participantstimes are UTC
Highlights from this day
- impersonator_ip — genuine question changed my mind on the four week rule, i think it depends entirely on how the current dose feels, happy to be corrected 20:28
- impersonator_ip — i dont think the plateau is a dose problem most of the time, but i cant prove that 20:49
- maintenance_mo — did anybody find a difference between BCH and pharmacy at the same 2.4 21:42
- month_six_me — how did people handle the jump from 1 to 1.7 22:19
- knees_first — my Janoshik report on the QST vial came back 99.2 against a certificate saying 98.6 22:25
the plateau hit me at 5 weeks and moved again about a month later without a dose change
follow up does anyone actually run a five week step instead of four
does moving my dose day by two days matter with a seven day half life
lost about 28kg on the low doses before i even got to 1, which surprised me
give it four weeks
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
£240 a month for compounded against what brand costs locally is why most people here use vials
my dose day drifted from friday to sunday, does that reset anything
my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
genuine question changed my mind on the four week rule, i think it depends entirely on how the current dose feels, happy to be corrected
⚠️13👀6
how long till steady state, ive read the half life is about a week
Inter-lab diff for lot H-2814: 98.1% vs 96.8%. Within expected range.
impersonator_ipgenuine question changed my mind on the four week rule, i think it depends entirely on…
compounded and brand felt the same to me at 10, which is one person and nothing more
ok so held at 10 and lost 32lb over 4 months, slower than the trials and fine by me
i dont think the plateau is a dose problem most of the time, but i cant prove that
STEP is several trials, so saying STEP said x is usually wrong without a number after it
is the plateau usually appetite coming back or just the scale stopping
*PeptideMeter not the other one
not the same trial
[edited]plateaus move
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going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
vial units and pen clicks are different systems, mixing the two is how people end up wrong
my plateau was the scale stopping while appetite stayed suppressed, which is a different problem, anyway
slower worked better
update on the earlier thing licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose
update on the earlier thing im 9 months in at 2.5 and the appetite effect faded, is that a thing
did anybody find a difference between BCH and pharmacy at the same 2.4
🙏3
the appetite effect faded for me around 16 months and going up fixed it for a while
thats STEP 1
brand vs compounded, is there a difference people can actually feel
anyone compared their 4 vial dosing against the pen increments
the long half life flattens the trough more than people expect, i never felt a day seven dip
STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping
i held at 1 for 3 months and it was the best decision i made, anyway
how did people handle the jump from 1 to 1.7
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my Janoshik report on the QST vial came back 99.2 against a certificate saying 98.6
✅1🎉10
is the plateau at 6 weeks normal or am i doing something wrong
FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
did the STEP 4 withdrawal arm show what i think it showed
steady state takes weeks
mine faded too
same dose day
went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down, not advice obviously
13 months at 2.4 and the honest summary is diminishing returns after the first half