vialroom

#semaglutide 2025-04-19

Saturday14 messages3 participantstimes are UTC
Highlights from this day
  • two_four_ceiling — changed my mind on the four week rule, i think it depends entirely on how the current dose feels 07:56
  • triumph_watch — is the plateau usually appetite coming back or just the scale stopping 08:23
  • two_four_ceiling — £120 a month for compounded against what brand costs locally is why most people here use vials, ill dig out the number 09:25
  • two_four_ceiling — STEP is several trials, so saying STEP said x is usually wrong without a number after it 09:51
  • triumph_watch — FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure 10:02
TF

changed my mind on the four week rule, i think it depends entirely on how the current dose feels

😂6👍11👀7
TW

is the plateau usually appetite coming back or just the scale stopping

7🎉3📈6
TF

went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down

TF

£120 a month for compounded against what brand costs locally is why most people here use vials, ill dig out the number

thats STEP 1

🔥13⚠️1🎉4

STEP is several trials, so saying STEP said x is usually wrong without a number after it

Cited study
Once-Weekly Semaglutide in Adults with Overweight or Obesity and Type 2 Diabetes (STEP 2)
The Lancet · 2021
The type 2 diabetes population, where the weight response is generally smaller.

im at 15 and stuck, did anyone break a plateau without going up

TW

FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure

wk 1-4    0.25mg
wk 5-10   0.50mg   (held 2 extra weeks)
wk 11-14  1.00mg
wk 15-26  1.70mg   (held, long)
wk 27+    2.40mg
KF

was SURMOUNT-OSA the one that ran to 68 weeks or am i mixing them up