#semaglutide 2025-04-10

Thursday15 messages5 participantstimes are UTC

Highlights from this day

fridge_thermo — my 10 vial in 5ml gives 8mg/ml so 0.25 lands on 20 units, thats why i picked that volume, your mileage will differ 11:32
mood_dip_mari — five week steps worked better for me than four, purely on how the second week felt, i have it written down somewhere 11:44
two_lifts_a_week — unrelated but half life is about a week so youre roughly four to five weeks to steady state on any new dose 12:00
cricket_or_footy — if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule 12:59
void_volume — FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure 13:13

my 10 vial in 5ml gives 8mg/ml so 0.25 lands on 20 units, thats why i picked that volume, your mileage will differ

wk 1-4    0.25mg
wk 5-10   0.50mg   (held 2 extra weeks)
wk 11-14  1.00mg
wk 15-26  1.70mg   (held, long)
wk 27+    2.40mg

mine faded too

the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing

five week steps worked better for me than four, purely on how the second week felt, i have it written down somewhere

2.4 is the ceiling

📈11

unrelated but half life is about a week so youre roughly four to five weeks to steady state on any new dose

not the same trial

seven days ish

SELECT wasnt weight

if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule

same dose day

does anyone actually run a five week step instead of four

is the plateau usually appetite coming back or just the scale stopping

FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure

🧊1🤝16

plateaus move

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