the plateau hit me at 7 weeks and moved again about a month later without a dose change
#semaglutide 2025-03-27
Thursday26 messages8 participantstimes are UTC
Highlights from this day
- sulphur_burp — follow up moving my dose day by a day or two never did anything noticeable for me 20:43
- sulphur_burp — my 15 vial in 1ml gives 2.5mg/ml so 2 lands on 8 units, thats why i picked that volume compounded and brand felt the same to me at 5, which is one person and nothing… 21:29
- underfill_uma — sorry to jump in dose day is sunday for me only because thats when i remember, not because sunday matters 23:16
how long till steady state, ive read the half life is about a week
restarted after 14 months off at a low dose and the nausea arrived exactly like the first time
follow up moving my dose day by a day or two never did anything noticeable for me
😂15👍1
STEP 1 ran to 68 weeks. thats the one everyone half remembers
SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
i stayed on 1.7 for 6 months and never went to 2.4, appetite was already where i needed it
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
steady state takes weeks
brand vs compounded, is there a difference people can actually feel
coming back to this did the STEP 4 withdrawal arm show what i think it showed
my 15 vial in 1ml gives 2.5mg/ml so 2 lands on 8 units, thats why i picked that volume
compounded and brand felt the same to me at 5, which is one person and nothing more
five week steps worked better for me than four, purely on how the second week felt, thats just me
vials not pens here
thats STEP 1
FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
compounded and brand felt the same to me at 2.4, which is one person and nothing more
held at 0.25 and lost 69lb over 23 months, slower than the trials and fine by me
my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
the appetite effect faded for me around 24 months and going up fixed it for a while
is 2.4 the top or do people go past it
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
the long half life flattens the trough more than people expect, i never felt a day seven dip
same dose day
i dont think the plateau is a dose problem most of the time, but i cant prove that
sorry to jump in dose day is sunday for me only because thats when i remember, not because sunday matters