10 months at 2.4 and the honest summary is diminishing returns after the first half, still working it out
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#semaglutide 2025-03-25
Tuesday12 messages4 participantstimes are UTC
Highlights from this day
- gradient_greg — 10 months at 2.4 and the honest summary is diminishing returns after the first half, still working it out 16:01
- two_four_ceiling — ok so was STEP 1 the one that ran to 68 weeks or am i mixing them up 16:36
- two_four_ceiling — licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose, not advice obviously 16:38
FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
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coming back to this im 21 months in at 2.5 and the appetite effect faded, is that a thing
[edited]weights-monthly.csv
158 rows · not retained in the public archive
half life is about a week so youre roughly four to five weeks to steady state on any new dose
ok so was STEP 1 the one that ran to 68 weeks or am i mixing them up
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licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose, not advice obviously
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mine faded too
STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping
whats the actual licensed ceiling, i keep seeing different numbers
slower worked better
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compounded and brand felt the same to me at 2.4, which is one person and nothing more
im at 12 and stuck, did anyone break a plateau without going up