my VendorInvestigate report on the SGN vial came back 97.4 against a certificate saying 99.4
#semaglutide 2025-02-11
Tuesday21 messages5 participantstimes are UTC
Highlights from this day
- relabel_watch — my VendorInvestigate report on the SGN vial came back 97.4 against a certificate saying 99.4 20:37
- first_and_last_four — did the STEP 4 withdrawal arm show what i think it showed 20:59
- quiet_head_qi — sorry to jump in the plateau hit me at 25 weeks and moved again about a month later without a dose change 21:17
- madrid_mg — for the archive how long till steady state, ive read the half life is about a week the trials titrated on a fixed schedule, most people here dont, worth remembering… 21:32
- relabel_watch — for the archive the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing 22:48
20:47tenpence pinned a message to this channel
2.4 is the ceiling
did the STEP 4 withdrawal arm show what i think it showed
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
compounded and brand felt the same to me at 15, which is one person and nothing more
sorry to jump in the plateau hit me at 25 weeks and moved again about a month later without a dose change
steady state takes weeks
is there a reason to hold at 1.7 rather than going to 2.4
for the archive i held at 15 for 4 months and it was the best decision i made
for the archive how long till steady state, ive read the half life is about a week
the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing
does moving my dose day by two days matter with a seven day half life
half life is about a week so youre roughly four to five weeks to steady state on any new dose
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
im 16 months in at 2 and the appetite effect faded, is that a thing
[edited]not the same trial
thats STEP 1
whats the actual licensed ceiling, i keep seeing different numbers
i stayed on 1.7 for 18 months and never went to 2.4, appetite was already where i needed it
does the seven day half life mean the last two days are weaker
my 5 vial in 2ml gives 4mg/ml so 15 lands on 15 units, thats why i picked that volume
for the archive the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing