does the licensed ceiling for weight differ from the diabetes one
#semaglutide 2024-09-22
Sunday39 messages7 participantstimes are UTC
Highlights from this day
- private_script_pri — im at 10 and stuck, did anyone break a plateau without going up 14:33
- rezept_rolf — half life is about a week so youre roughly four to five weeks to steady state on any new dose 15:56
- protein_floor — is the plateau usually appetite coming back or just the scale stopping 16:01
- protein_floor — my Medutest report on the GL Biochem vial came back 97.4 against a certificate saying 99 16:35
steady state takes weeks
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
anyone compared their 5 vial dosing against the pen increments
is 2.4 the top or do people go past it
FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
mine faded too
Batch lookup D-0718: 6 independent reports on file, earliest 2024-01-01.
restarted after 23 months off at a low dose and the nausea arrived exactly like the first time
compounded and brand felt the same to me at 7.5, which is one person and nothing more
went too fast once
the plateau hit me at 11 weeks and moved again about a month later without a dose change
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SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
is there a reason to hold at 1.7 rather than going to 2.4
plateaus move
steady state is the bit people skip, judging a new dose after eight days tells you almost nothing
not the same trial
SELECT wasnt weight
i dont think the plateau is a dose problem most of the time, but i cant prove that
went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down, n of 1 obviously
thats STEP 1
im at 10 and stuck, did anyone break a plateau without going up
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seven days ish
dose day is sunday for me only because thats when i remember, not because sunday matters, thats just me
the appetite effect faded for me around 4 months and going up fixed it for a while
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held there too
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while im here €72 a month for compounded against what brand costs locally is why most people here use vials
the long half life flattens the trough more than people expect, i never felt a day seven dip
vial units and pen clicks are different systems, mixing the two is how people end up wrong
does moving my dose day by two days matter with a seven day half life
how long till steady state, ive read the half life is about a week
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licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose
half life is about a week so youre roughly four to five weeks to steady state on any new dose
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lost about 20kg on the low doses before i even got to 1, which surprised me, thats just me
is the plateau usually appetite coming back or just the scale stopping
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STEP is several trials, so saying STEP said x is usually wrong without a number after it
give it four weeks
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my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
my Medutest report on the GL Biochem vial came back 97.4 against a certificate saying 99
does the seven day half life mean the last two days are weaker