does moving my dose day by two days matter with a seven day half life
#semaglutide 2024-08-18
Sunday46 messages10 participantstimes are UTC
Highlights from this day
- LC_MS_Lena — brand vs compounded, is there a difference people can actually feel 22:22
- blank_slate_bo — the appetite effect faded for me around 23 months and going up fixed it for a while 22:24
- LC_MS_Lena — the long half life flattens the trough more than people expect, i never felt a day seven dip 22:25
- triple_ag_tom — follow up did anyone titrate slower than four weeks a step and how did that go 23:01
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
brand vs compounded, is there a difference people can actually feel
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the appetite effect faded for me around 23 months and going up fixed it for a while
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the long half life flattens the trough more than people expect, i never felt a day seven dip
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not the same trial
changed my mind on the four week rule, i think it depends entirely on how the current dose feels
my 10 vial in 3ml gives 4mg/ml so 15 lands on 25 units, thats why i picked that volume
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does the licensed ceiling for weight differ from the diabetes one
slower worked better
how long till steady state, ive read the half life is about a week
anyone gone from 10 straight to 0.25 or is that too big a jump
while im here STEP is several trials, so saying STEP said x is usually wrong without a number after it
follow up is the plateau usually appetite coming back or just the scale stopping
STEP 1 ran to 68 weeks. thats the one everyone half remembers, ill dig out the number
my Medutest report on the QYB vial came back 97.4 against a certificate saying 96.8
my dose day drifted from friday to sunday, does that reset anything
for the archive i dont think the plateau is a dose problem most of the time, but i cant prove that
went too fast once
my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
coming back to this did anyone hold at 7.5 longer than four weeks before going up
£55 a month for compounded against what brand costs locally is why most people here use vials, i could be wrong
does anyone actually run a five week step instead of four
the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing
[edited]follow up did anyone titrate slower than four weeks a step and how did that go
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right so steady state is the bit people skip, judging a new dose after eight days tells you almost nothing
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held at 5 and lost 25lb over 22 months, slower than the trials and fine by me, i think
dose day is sunday for me only because thats when i remember, not because sunday matters
how long did the first 14kg take for people at the low doses
went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step
how many weeks before you noticed anything at 1
half life is about a week so youre roughly four to five weeks to steady state on any new dose
moving my dose day by a day or two never did anything noticeable for me
same dose day
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compounded and brand felt the same to me at 0.25, which is one person and nothing more
im 10 months in at 7.5 and the appetite effect faded, is that a thing
half life is about a week so youre roughly four to five weeks to steady state on any new dose
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
mine faded too
lost about 21kg on the low doses before i even got to 1, which surprised me, i could be wrong
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i held at 2.4 for 9 months and it was the best decision i made
STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping
slightly off topic but anyone compared their 4 vial dosing against the pen increments
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thats STEP 1
is 2.4 the top or do people go past it
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was STEP 1 the one that ran to 68 weeks or am i mixing them up