sat at 0.5 for 6 months rather than climbing and it kept working, so i never went up, thats one data point
#retatrutide 2026-05-25
Monday44 messages8 participantstimes are UTC
Highlights from this day
- electrolyte_eli — right so i said 8 months ago that my heart rate had settled and it has stayed settled since, take that with a pinch of salt 15:24
- electrolyte_eli — no idea whether the heart rate settles for everyone, mine did and one log isnt data 16:52
- wrong_network — ok so i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind 17:47
- ghk_gia — for the archive my resting heart rate is up about 6 bpm, did that settle for anyone 17:56
phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan
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whats the half life like, is it weekly the same way
held mine ages
smaller steps here
PeptideMeter came back 99.4 on one lot and 97.4 on the next from the same HJ, both fine
is there any long term safety data at all or is it phase 2 and hope
no long term data
nobody should read my log as a plan, im recording what i did and thats all it is
low and slow
buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely
14:45chlorhex pinned a message
does the glucagon arm explain the heart rate or is that unrelated
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists
research use only is on every vial and i treat it as exactly that, nobody here is prescribing
stopped for 17 months and restarted at half my old dose, the ramp was easier second time
electrolyte_elisat at 0.5 for 6 months rather than climbing and it kept working, so i never went up,…
phase 2 was still trending at the end which is why the phase 3 readout matters more than usual, your mileage will differ
im at 1.7 and the appetite effect is stronger than i expected, normal
did the phase 2 result actually come in higher than the tirzepatide numbers
ok so why does everyone insist on smaller steps here than on the other two
logging rhr daily
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right so i said 8 months ago that my heart rate had settled and it has stayed settled since, take that with a pinch of salt
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triple agonist yeah
research use only
anyone gone above 1.7 and what changed
is the phase 2 dosing anywhere near what people here run
anyone tracking blood pressure alongside the heart rate
anyone logging resting heart rate on this
the honest position is this has less human evidence behind it than anything else discussed here
phase 2 only
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial
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no idea whether the heart rate settles for everyone, mine did and one log isnt data
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appetite suppression at 1 was stronger than my tirzepatide experience at a comparable point
TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
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mine went up too
ok so i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
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the heart rate thing is real enough that i mention it whenever someone asks about starting
glucagon is the new bit
came off at 12 weeks because my resting rate stayed elevated and i didnt like it
for the archive my resting heart rate is up about 6 bpm, did that settle for anyone
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cant feel it honestly
settled by month three
my resting rate went up 9 bpm in the first month and came back most of the way by month 21