no long term data
#retatrutide 2025-07-23
Wednesday32 messages8 participantstimes are UTC
Highlights from this day
- vial_ledger — sorry to jump in appetite suppression at 2 was stronger than my tirzepatide experience at a comparable point 14:23
- triple_ag_tom — genuine question energy expenditure isnt something i could feel, though my sleep tracker disagreed with me 14:38
- customs_owl — VendorInvestigate came back 98.6 on one lot and 99.4 on the next from the same ERP, both fine 14:57
- triple_ag_tom — the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me 14:59
- triple_ag_tom — blood pressure stayed flat for me while heart rate moved, which i didnt expect 15:25
reconstituted the 15 vial to 4mg/ml specifically so i could take 0.5 without measuring crumbs
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists
triple agonist yeah
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whats the half life like, is it weekly the same way
GI was about the same as tirzepatide for me, the difference was how fast it arrived
sorry to jump in appetite suppression at 2 was stronger than my tirzepatide experience at a comparable point
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held mine ages
anyone logging resting heart rate on this
genuine question energy expenditure isnt something i could feel, though my sleep tracker disagreed with me
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TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule
my resting heart rate is up about 6 bpm, did that settle for anyone
how slow is low and slow here, four weeks a step or longer
VendorInvestigate came back 98.6 on one lot and 99.4 on the next from the same ERP, both fine
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
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*Janoshik not the other one
people insist on small steps because the side effects arrive faster than on the other two
logging rhr daily
15:05ferrous_ash pinned a message to this channel
research use only
phase 2 only
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blood pressure stayed flat for me while heart rate moved, which i didnt expect
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low and slow
i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps
i said 8 months ago that my heart rate had settled and it has stayed settled since
is TRIUMPH the phase 3 programme
lost 32kg over 12 months at doses well under what the trials used
settled by month three
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held at 1.7 for 5 months and it never plateaued for me, which i cant explain
i log resting heart rate every morning because of this and its the one number i actually watch
17:07ferrous_ash pinned a message to this channel