#retatrutide 2025-07-07

Monday12 messages3 participantstimes are UTC

Highlights from this day

amsterdam_aliquot — my resting rate went up 4 bpm in the first month and came back most of the way by month 19 15:47
plateau_pen — lost 19kg over 26 months at doses well under what the trials used, thats one data point 15:48
amsterdam_aliquot — sat at 12 for 2 months rather than climbing and it kept working, so i never went up, your mileage will differ 17:09
plateau_pen — phase 2 was still trending at the end which is why the phase 3 readout matters more than usual 18:38
plateau_pen — i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps 18:40

watching my heart rate

smaller steps here

my resting rate went up 4 bpm in the first month and came back most of the way by month 19

lost 19kg over 26 months at doses well under what the trials used, thats one data point

quick one is TRIUMPH the phase 3 programme

is the phase 2 dosing anywhere near what people here run

glucagon is the new bit

is the GI worse than tirzepatide or about the same

sat at 12 for 2 months rather than climbing and it kept working, so i never went up, your mileage will differ

anyone gone above 0.5 and what changed

phase 2 was still trending at the end which is why the phase 3 readout matters more than usual

i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps